Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.61 |
| ▸ | HTR2C | P28335 | 8/20 | 0.61 |
| ▸ | HTR2B | P41595 | 8/20 | 0.61 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29788066 | 1.00 | HTR2A (0.61) | HTR2AHTR2CHTR2BCD274MAOA | |
| Hydrochloric Acid SCHEMBL915156 | 0.98 | HTR2A (0.59) | HTR2AHTR2CHTR2BCD274MAOA | |
| Hydrochloric Acid SCHEMBL7075718 | 0.96 | HTR2A (0.58) | HTR2AHTR2CHTR2BCD274MAOA | |
| Sulfuric Acid SCHEMBL28482842 | 0.89 | HTR2A (0.51) | HTR2AHTR2CHTR2BCD274MAOA | |
| SCHEMBL3162737 | 0.89 | HTR2A (0.74) | HTR2AHTR2CHTR2BMAOATSHR | |
| SCHEMBL24620372 | 0.89 | HTR2A (0.54) | HTR2AHTR2CHTR2BCD274PNMT | |
| SCHEMBL14615343 | 0.89 | HTR2A (0.54) | HTR2AHTR2CHTR2BCD274PNMT | |
| SCHEMBL21850578 | 0.89 | HTR2A (0.54) | HTR2AHTR2CHTR2BCD274PNMT | |
| SCHEMBL19773028 | 0.89 | HTR2A (0.54) | HTR2AHTR2CHTR2BCD274PNMT | |
| SCHEMBL22048865 | 0.88 | HTR2C (0.49) | HTR2AHTR2CHTR2BCD274MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 724 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307497-A | Terephthalamide antitumor compound and preparation method and application thereof | 江苏海洋大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118126114-A | Sigma2 ligand and preparation method and application thereof | 中国人民解放军空军军医大学 | 2024-06-04 | — | — | CN | claimed |
| CN-118027033-A | HDAC6 inhibitor, preparation method thereof and application thereof in anti-inflammatory and ulcerative colitis | 四川大学 | 2024-05-14 | — | — | CN | claimed |
| CN-115286616-A | Tetrahydroisoquinoline and isoindoline compound capable of binding sigma-2 receptor, preparation method and application thereof | 北京师范大学 | 2022-11-04 | — | — | CN | claimed |
| CN-112851679-B | 2, 4, 7-trisubstituted pyrimidoindole compound with antitumor effect | 广东医科大学 | 2022-03-25 | — | — | CN | claimed |
| CN-111621805-B | Method for preparing 3, 4-dihydroisoquinoline by electrocatalytic selective dehydrogenation | 天津大学 | 2022-02-18 | — | — | CN | claimed |
| US-11034650-B2 | Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection | INTERVET INC. (US) | 2021-06-15 | — | — | US | claimed |
| CN-111621805-A | Method for preparing 3, 4-dihydroisoquinoline by electrocatalytic selective dehydrogenation | 天津大学 | 2020-09-04 | — | — | CN | claimed |
| CN-109678795-B | 4-carbamate-ferulamide-1, 2,3, 4-tetrahydroisoquinoline compounds and preparation method and application thereof | 南阳师范学院 | 2020-07-14 | — | — | CN | claimed |
| US-20200069811-A1 | PEPTIDE-BASED MULTIPLE-DRUG DELIVERY VEHICLE | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2020-03-05 | — | — | US | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| WO-2000050406-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | LION BIOSCIENCE AG (DE) | 2000-08-31 | — | — | WO | claimed |
| EP-0673782-B1 | Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds | XEROX CORP (US) | 2000-06-14 | — | — | EP | claimed |
| EP-0863877-A4 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INST (US) | 1999-07-21 | — | — | EP | claimed |
| US-5874443-A | BIOSYNTHESIS | TREGA BIOSCIENCES, INC. (US) | 1999-02-23 | — | — | US | claimed |
| EP-0863877-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1998-09-16 | — | — | EP | claimed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | claimed |
| EP-0338352-A2 | Salicylic acid derivatives | MERCK PATENT GmbH (DE) | 1989-10-25 | — | — | EP | claimed |
| EP-0109039-B1 | BENZO(F)QUINOLINE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-02-25 | — | — | EP | claimed |
| US-4556656-A | HYPOTENSIVE, ANTIPSYCHOTIC, DIABETIC, AND ANALGESIC AGENTS | THE UPJOHN COMPANY (US) | 1985-12-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11034650-B2 | Compounds useful for treating a Mannheimia haemolytica or Histophilus somni infection | HEXD, SORD, SDHA | HTR2A 2518/4885HTR2C 2823/4885HTR2B 1790/4885 |
| US-20200069811-A1 | PEPTIDE-BASED MULTIPLE-DRUG DELIVERY VEHICLE | VIP, NGLY1, IAPP | HTR2A 3706/4885HTR2C 4222/4885HTR2B 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.