Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 7/20 | 0.59 |
| ▸ | HTR2C known ✓ | P28335 | 7/20 | 0.59 |
| ▸ | HTR2B known ✓ | P41595 | 7/20 | 0.59 |
| ▸ | MAOA known ✓ | P21397 | 2/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329913 | 0.98 | HTR2A (0.61) | HTR2AHTR2CHTR2BMAOACD274 | |
| SCHEMBL29788066 | 0.98 | HTR2A (0.61) | HTR2AHTR2CHTR2BMAOACD274 | |
| Hydrochloric Acid SCHEMBL7075718 | 0.94 | HTR2A (0.58) | HTR2AHTR2CHTR2BMAOACD274 | |
| Hydrochloric Acid SCHEMBL4247274 | 0.90 | HTR2A (0.71) | HTR2AHTR2CHTR2BMAOATSHR | |
| Sulfuric Acid SCHEMBL28482842 | 0.88 | HTR2A (0.51) | HTR2AHTR2CHTR2BMAOACD274 | |
| Hydrochloric Acid SCHEMBL5600142 | 0.88 | MAOA (0.54) | HTR2AHTR2CHTR2BMAOA | |
| Hydrochloric Acid SCHEMBL29693499 | 0.88 | HTR2A (0.57) | HTR2AHTR2CHTR2BCD274PNMT | |
| Hydrochloric Acid SCHEMBL5600419 | 0.88 | MAOA (0.54) | HTR2AHTR2CHTR2BMAOA | |
| SCHEMBL3162737 | 0.87 | HTR2A (0.74) | HTR2AHTR2CHTR2BMAOATSHR | |
| SCHEMBL24620372 | 0.87 | HTR2A (0.54) | HTR2AHTR2CHTR2BCD274PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010913-A | Rhodamine-marked isoquinoline derivative and preparation method and application thereof | 淮阴师范学院 | 2026-05-12 | — | — | CN | claimed |
| CN-115626918-B | Phenyl furan-tetrahydroisoquinoline compound and preparation and application thereof | 浙江工业大学 | 2024-11-05 | — | — | CN | claimed |
| CN-117229207-B | Phenyl naphthalene compound and preparation and application thereof | 浙江工业大学 | 2024-09-03 | — | — | CN | claimed |
| CN-115745961-B | Phenyl indole compound and preparation and application thereof | 浙江工业大学 | 2024-03-26 | — | — | CN | claimed |
| CN-115716818-B | Benzamide compound and preparation and application thereof | 浙江工业大学 | 2024-02-13 | — | — | CN | claimed |
| CN-117229207-A | Phenyl naphthalene compound and preparation and application thereof | 浙江工业大学 | 2023-12-15 | — | — | CN | claimed |
| CN-115745961-A | Phenyl indole compound and preparation and application thereof | 浙江工业大学 | 2023-03-07 | — | — | CN | claimed |
| CN-115716818-A | Benzamide compound and preparation and application thereof | 浙江工业大学 | 2023-02-28 | — | — | CN | claimed |
| CN-115626918-A | Phenyl furan-tetrahydroisoquinoline compound and preparation and application thereof | 浙江工业大学 | 2023-01-20 | — | — | CN | claimed |
| CN-112552290-B | Amido bond-containing phenylfuran-2-tetrahydroisoquinoline compound and preparation method and application thereof | 浙江工业大学 | 2022-10-11 | — | — | CN | claimed |
| CN-112552290-A | Amido bond-containing phenylfuran-2-tetrahydroisoquinoline compound and preparation method and application thereof | 浙江工业大学 | 2021-03-26 | — | — | CN | claimed |
| CN-112480076-A | Phenylpyridine compound and preparation and application thereof | 浙江工业大学 | 2021-03-12 | — | — | CN | claimed |
| CN-112480094-A | Thiophene 2, 5-disubstituted-tetrahydroisoquinoline compounds, and preparation and application thereof | 浙江工业大学 | 2021-03-12 | — | — | CN | claimed |
| CN-112480091-A | Furan ring 2, 5-disubstituted-tetrahydroisoquinoline compound and its preparation and use | 浙江工业大学 | 2021-03-12 | — | — | CN | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |