Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.58 |
| ▸ | HTR2C | P28335 | 8/20 | 0.58 |
| ▸ | HTR2B | P41595 | 8/20 | 0.58 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29788066 | 0.96 | HTR2A (0.61) | HTR2AHTR2CHTR2BCD274MAOA | |
| SCHEMBL329913 | 0.96 | HTR2A (0.61) | HTR2AHTR2CHTR2BCD274MAOA | |
| Hydrochloric Acid SCHEMBL915156 | 0.94 | HTR2A (0.59) | HTR2AHTR2CHTR2BCD274MAOA | |
| Sulfuric Acid SCHEMBL28482842 | 0.86 | HTR2A (0.51) | HTR2AHTR2CHTR2BCD274MAOA | |
| SCHEMBL3162737 | 0.86 | HTR2A (0.74) | HTR2AHTR2CHTR2BMAOATSHR | |
| SCHEMBL24620372 | 0.85 | HTR2A (0.54) | HTR2AHTR2CHTR2BCD274PNMT | |
| SCHEMBL21850578 | 0.85 | HTR2A (0.54) | HTR2AHTR2CHTR2BCD274PNMT | |
| SCHEMBL19773028 | 0.85 | HTR2A (0.54) | HTR2AHTR2CHTR2BCD274PNMT | |
| SCHEMBL14615343 | 0.85 | HTR2A (0.54) | HTR2AHTR2CHTR2BCD274PNMT | |
| SCHEMBL22048865 | 0.85 | HTR2C (0.49) | HTR2AHTR2CHTR2BCD274MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105073-A1 | Quinolone derivatives | CELLTECH R&D LIMITED (GB) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105073-A1 | Quinolone derivatives | IFNAR1, CBR1, IMPDH1 | HTR2A 3698/4885HTR2C 2332/4885HTR2B 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.