Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 7/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537810 | 0.94 | TSHR (0.48) | TSHRTHRBACHENAAAALDH1A1 | |
| SCHEMBL8536455 | 0.92 | TSHR (0.52) | TSHRTHRBACHENAAAALDH1A1 | |
| SCHEMBL9646938 | 0.89 | TSHR (0.55) | TSHRTHRBACHENAAAALDH1A1 | |
| SCHEMBL19456885 | 0.89 | TSHR (0.50) | TSHRTHRBACHENAAAALDH1A1 | |
| SCHEMBL173351 | 0.87 | TSHR (0.41) | TSHRTHRBACHENAAAALDH1A1 | |
| SCHEMBL375032 | 0.85 | TSHR (0.57) | TSHRTHRBACHENAAAALDH1A1 | |
| Ethylene Glycol SCHEMBL5469504 | 0.85 | TSHR (0.62) | TSHRTHRBACHENAAAALDH1A1 | |
| SCHEMBL57345 | 0.84 | THRB (0.50) | TSHRTHRBACHENAAAALDH1A1 | |
| SCHEMBL31390457 | 0.84 | TSHR (0.47) | TSHRTHRBACHENAAAALDH1A1 | |
| SCHEMBL374970 | 0.83 | TSHR (0.66) | TSHRACHENAAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101552-A | A kind of copolymer ceramic green body reinforcing agent and its ATRP the preparation methods based on cyclodextrin | 湖南辰砾新材料有限公司 | 2018-06-01 | — | — | CN | claimed |
| CN-104136012-A | Method for preparing nanoparticles loaded with active substance | MERCK PATENT GMBH | 2014-11-05 | — | — | CN | claimed |
| CN-1930208-A | Compositions useful as coatings, their preparation, and articles made therefrom | GEN ELECTRIC (US) | 2007-03-14 | — | — | CN | claimed |
| EP-1709100-A1 | COMPOSITIONS USEFUL AS COATINGS, THEIR PREPARATION, AND ARTICLES MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2006-10-11 | — | — | EP | claimed |
| WO-2005073271-A1 | COMPOSITIONS USEFUL AS COATINGS, THEIR PREPARATION, AND ARTICLES MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2005-08-11 | — | — | WO | claimed |
| US-20050159542-A1 | Compositions useful as coatings, their preparation, and articles made therefrom | GENERAL ELECTRIC COMPANY | 2005-07-21 | — | — | US | claimed |
| CN-108101552-B | Copolymer ceramic body reinforcing agent based on cyclodextrin and ATRP preparation method thereof | 湖南辰砾新材料有限公司 | 2020-03-27 | — | — | CN | disclosed |
| CN-104136012-B | Method for preparing nanoparticles loaded with active substance | 默克专利股份有限公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-108101552-A | A kind of copolymer ceramic green body reinforcing agent and its ATRP the preparation methods based on cyclodextrin | 湖南辰砾新材料有限公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-104136012-A | Method for preparing nanoparticles loaded with active substance | MERCK PATENT GMBH | 2014-11-05 | — | — | CN | disclosed |
| CN-103768582-A | Neuregulin capable of improving heat function when continually administrated | ZENSUN SHANGHAI SCI & TECH CO LTD | 2014-05-07 | — | — | CN | disclosed |
| CN-101394861-A | Sustained administration of neuregulin can improve cardiac function | ZENSUN SHANGHAI SCIENCE & TECH (CN) | 2009-03-25 | — | — | CN | disclosed |