Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206642 | 0.88 | NPC1 (0.49) | ALDH1A1L3MBTL1NPC1HPGDMAPT | |
| SCHEMBL12411252 | 0.88 | NPC1 (0.49) | ALDH1A1L3MBTL1NPC1HPGDMAPT | |
| SCHEMBL7944757 | 0.85 | ALDH1A1 (0.48) | ALDH1A1CYP2A6MAPTTSHRALDH3A1 | |
| SCHEMBL9804059 | 0.80 | CYP19A1 (0.47) | ALDH1A1L3MBTL1NPC1HPGDMAPT | |
| SCHEMBL9798372 | 0.79 | TDP1 (0.47) | NPC1HPGDLMNATDP1GAA | |
| SCHEMBL9615237 | 0.76 | MEN1 (0.41) | ALDH1A1CYP2A6L3MBTL1NPC1TSHR | |
| SCHEMBL629143 | 0.75 | ALDH1A1 (0.52) | ALDH1A1CYP2A6L3MBTL1NPC1HPGD | |
| SCHEMBL12172154 | 0.74 | ESR1 (0.64) | ALDH1A1CYP2A6HPGDMAPTTSHR | |
| Benzaldehyde SCHEMBL9780149 | 0.73 | ALDH1A1 (0.70) | ALDH1A1CYP2A6L3MBTL1NPC1TSHR | |
| Benzaldehyde SCHEMBL27520789 | 0.73 | ALDH1A1 (0.78) | ALDH1A1CYP2A6L3MBTL1NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052291-B1 | Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it | CANON KK (JP) | 2006-10-25 | — | — | EP | disclosed |
| EP-0684239-B1 | A method for detecting a target substance in a sample, utilizing pyrylium compound | CANON KK (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-0643140-B1 | Determination of nucleic acid by PCR, measurement of number of microbial cells, genes, or gene-copies by PCR, and measuring-kit employed for the same | CANON KK (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-0603783-B1 | Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it | CANON KK (JP) | 2001-09-26 | — | — | EP | disclosed |
| US-6242477-B1 | RADIATING AND KILLING CANCER CELLS | CANON KABUSHIKI KAISHA (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6156506-A | Method for detecting a target substance in a sample, utilizing pyrylium compound | CANON KABUSHIKI KAISHA (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-1052291-A2 | Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it | CANON KABUSHIKI KAISHA (JP) | 2000-11-15 | — | — | EP | disclosed |
| US-6124342-A | RADIATION THERAPY TO INDUCE DEATH OF THE CANCER CELLS | CANON KK (JP) | 2000-09-26 | — | — | US | disclosed |
| US-6022961-A | HYBRIDIZATION PROBE OF SINGLE-STRANDED NUCLEIC ACID HAVING NUCLEOTIDE SEQUENCE COMPLEMENTARY TO TARGET AND WITH COVALENTLY BOUND DYE | CANON KABUSHIKI KAISHA (JP) | 2000-02-08 | — | — | US | disclosed |
| US-5670315-A | AMPLIFICATION; QUANTITATIVE ANALYSIS | CANON KABUSHIKI KAISHA (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5624798-A | Detection method of nucleic acid by use of fluorescent pyrylium stain in intercalation into nucleic acids | CANON KABUSHIKI KAISHA (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0684239-A1 | A method for detecting a target substance in a sample, utilizing pyrylium compound | CANON KABUSHIKI KAISHA (JP) | 1995-11-29 | — | — | EP | disclosed |
| EP-0659407-A1 | Pharmaceutical compositions containing pyrylium compounds, pyrylium salts and process for manufacturing a medicament containing the aforesaid compounds | CANON KABUSHIKI KAISHA (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0643140-A1 | Determination of nucleic acid by PCR, measurement of number of microbial cells, genes, or gene-copies by PCR, and measuring-kit employed for the same | CANON KABUSHIKI KAISHA (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0603783-A1 | Fluorescent stain containing pyrylium salt or its similar salt, detection method of nucleic acid by use of it, and fluorescent staining method of biological sample | CANON KABUSHIKI KAISHA (JP) | 1994-06-29 | — | — | EP | disclosed |