Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499677 | 0.88 | LMNA (0.47) | TDP1LMNAKCNH2GAAHPGD | |
| SCHEMBL2428644 | 0.88 | LMNA (0.47) | TDP1LMNAKCNH2GAAHPGD | |
| SCHEMBL6379933 | 0.84 | HPGD (0.45) | TDP1LMNAGAAHPGDCES2 | |
| SCHEMBL6090753 | 0.84 | HPGD (0.45) | TDP1LMNAGAAHPGDCES2 | |
| SCHEMBL5709306 | 0.79 | ALDH1A1 (0.47) | TDP1LMNAGAAHPGDNPC1 | |
| SCHEMBL3146684 | 0.78 | MLYCD (0.49) | TDP1LMNAGAAHPGDCES1 | |
| SCHEMBL3359317 | 0.78 | LMNA (0.46) | TDP1LMNAKCNH2TACR1 | |
| SCHEMBL5128478 | 0.78 | LMNA (0.41) | TDP1LMNAKCNH2GAAHPGD | |
| SCHEMBL13617659 | 0.77 | CNR2 (0.53) | GAAHPGDCNR2 | |
| SCHEMBL28927275 | 0.77 | CNR2 (0.53) | GAAHPGDCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411103-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK PATENT GmbH (DE) | 1991-02-06 | — | — | EP | disclosed |
| WO-1990009616-A1 | NON-LINEAR OPTICAL MATERIALS WITH VICINAL DONOR OR ACCEPTOR GROUPS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |