Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680729 | 0.90 | HSD11B1 (0.42) | HSD11B1ALDH1A1AKR1B1 | |
| SCHEMBL27660700 | 0.90 | HSD11B1 (0.42) | HSD11B1ALDH1A1AKR1B1 | |
| SCHEMBL5709364 | 0.90 | HSD11B1 (0.42) | HSD11B1ALDH1A1AKR1B1 | |
| SCHEMBL27680727 | 0.85 | HSD11B1 (0.39) | HSD11B1ALDH1A1AKR1B1P2RX7 | |
| SCHEMBL5709459 | 0.85 | HSD11B1 (0.39) | HSD11B1ALDH1A1AKR1B1P2RX7 | |
| SCHEMBL5709379 | 0.85 | HSD11B1 (0.39) | HSD11B1ALDH1A1AKR1B1P2RX7 | |
| SCHEMBL27680726 | 0.83 | HSD11B1 (0.43) | HSD11B1ALDH1A1AKR1B1 | |
| SCHEMBL5709361 | 0.83 | HSD11B1 (0.43) | HSD11B1ALDH1A1AKR1B1 | |
| SCHEMBL27680705 | 0.83 | HSD11B1 (0.43) | HSD11B1ALDH1A1AKR1B1 | |
| SCHEMBL5709422 | 0.82 | SLC6A9 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950328-A | Phenyl indan derivatives | LUNDBECK & CO AS H (DK) | 2007-04-18 | — | — | CN | disclosed |
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |