Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709439 | 0.87 | SLC6A4 (0.42) | SLC6A4TACR2TACR1TACR3SLC6A3 | |
| SCHEMBL5709391 | 0.79 | SLC6A4 (0.45) | SLC6A4TACR2TACR1TACR3SLC6A3 | |
| SCHEMBL5709328 | 0.72 | KDM1A (0.37) | SLC6A2 | |
| SCHEMBL5709388 | 0.72 | BCHE (0.42) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5709423 | 0.69 | BCHE (0.47) | — | |
| SCHEMBL5709380 | 0.69 | BCHE (0.36) | — | |
| SCHEMBL744195 | 0.68 | ADRA2A (0.42) | — | |
| SCHEMBL4784319 | 0.68 | KDM1A (0.46) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8706204 | 0.68 | MEN1 (0.49) | TACR2TACR1TACR3 | |
| SCHEMBL9545809 | 0.68 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |