Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL1191470 | 0.78 | CHRM3 (0.52) | HRH3CHRM3 | |
| SCHEMBL186785 | 0.78 | BCHE (0.67) | SIGMAR1ACHE | |
| SCHEMBL2408335 | 0.77 | SIGMAR1 (0.61) | HTR2ASIGMAR1ACHE | |
| SCHEMBL17440420 | 0.77 | CHRNB2 (0.58) | — | |
| SCHEMBL17440417 | 0.77 | CHRNB2 (0.58) | — | |
| Hydrochloric Acid SCHEMBL22587709 | 0.77 | BCHE (0.65) | SIGMAR1ACHE | |
| SCHEMBL8693567 | 0.76 | KCNA3 (0.61) | LMNA | |
| SCHEMBL3935469 | 0.76 | SIGMAR1 (0.67) | HTR2AHRH3SIGMAR1 | |
| Biphenyl SCHEMBL1191229 | 0.76 | CA1 (0.48) | LMNAPOLB | |
| Hydrochloric Acid SCHEMBL10969939 | 0.75 | HTR2A (0.54) | HTR2ALMNASIGMAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |