Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980719 | 0.86 | NPC1 (0.43) | POLBTDP1CES1CES2LMNA | |
| SCHEMBL8212756 | 0.81 | CES2 (0.48) | ALDH1A1HSD17B10TDP1CES1CES2 | |
| SCHEMBL4653279 | 0.80 | POLB (0.41) | POLBALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL6283617 | 0.77 | ALDH1A1 (0.41) | POLBALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL3011527 | 0.77 | ALDH1A1 (0.41) | POLBALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL8576250 | 0.77 | ATM (0.42) | POLBALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL8576252 | 0.77 | ATM (0.42) | POLBALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL7530850 | 0.75 | NR4A1 (0.50) | POLBALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL7698518 | 0.74 | CES1 (0.44) | POLBALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL9493195 | 0.74 | RIPK1 (0.44) | POLBALDH1A1TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103224474-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-07-31 | — | — | CN | claimed |
| CN-101861308-B | Process for the preparation of benzofuran compounds | CAMBREX KARLSKOGA AB | 2013-06-19 | — | — | CN | claimed |
| CN-101027279-B | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-03-27 | — | — | CN | claimed |
| CN-101855214-B | Benzimidazole derivatives and their use as FXR agonists | HOFFMANN LA ROCHE | 2012-12-26 | — | — | CN | claimed |
| CN-102091072-A | Nucleoside derivatives and therapeutic use thereof | REXAHN CORP | 2011-06-15 | — | — | CN | claimed |
| CN-1980898-B | Nucleoside derivatives and their therapeutic use | REXAHN CORP | 2011-01-12 | — | — | CN | claimed |
| CN-1989253-A | Method for producing enantiomeric forms of 3-hydroxycyclohexanecarboxylic acid derivatives in cis-configuration using a hydrolase | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-06-27 | — | — | CN | claimed |
| CN-1980898-A | Nucleoside derivatives and their therapeutic use | REXAHN CORP (US) | 2007-06-13 | — | — | CN | claimed |
| CN-106536045-B | Catalyst and process for preparing same | IP2IPO 创新有限公司 | 2020-02-07 | — | — | CN | disclosed |
| CN-106164076-B | Compound as ROS1 inhibitor | 詹森药业有限公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-106164076-A | As be replaced the 4 of ROS1 inhibitor, 5,6,7 tetrahydro-pyrazoles also [1,5 a] pyrazines derivatives and 5,6,7,8 tetrahydrochysene 4H pyrazolo [1,5 a] [Isosorbide-5-Nitrae] diazacyclo heptantriene derivants | 詹森药业有限公司 | 2016-11-23 | — | — | CN | disclosed |
| EP-1719615-B1 | PLATED RESIN FORMED ARTICLE | DAICEL POLYMER LTD (JP) | 2016-08-17 | — | — | EP | disclosed |
| CN-103342633-B | For the preparation of the method for benzofuran compounds | CAMBREX KARLSKOGA AB (SE) | 2016-05-04 | — | — | CN | disclosed |
| CN-102164899-B | Substituted indazoles or tetrahydroindazoles as FXR modulators against dyslipidemia and related diseases | HOFFMANN LA ROCHE | 2014-11-26 | — | — | CN | disclosed |
| CN-86102923-A | The method for preparing antibiotic derivatives | — | 1986-11-12 | — | — | CN | disclosed |
| CN-85109492-A | Tricyclic compounds, process for their production and pharmaceutical compositions containing them | — | 1986-06-10 | — | — | CN | disclosed |
| EP-0053815-A1 | 2-Oxoazetidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-16 | — | — | EP | disclosed |
| US-4305839-A | PHOSPHITES AND PHOSPHONITES FOR COLOR STABILITY | CARSTAB CORPORATION (US) | 1981-12-15 | — | — | US | disclosed |
| US-4297352-A | CEPHALOSPORINS; BACTERICIDES; ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1981-10-27 | — | — | US | disclosed |
| US-4260747-A | CEPHALOSPORINS, ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1981-04-07 | — | — | US | disclosed |