Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.55 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.53 |
| ▸ | TK2 | O00142 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071383 | 1.00 | RNASE1 (0.55) | RNASE1UPP1TK2TK1 | |
| SCHEMBL5710067 | 0.90 | RNASE1 (0.68) | RNASE1UPP1TK2TK1 | |
| SCHEMBL20833584 | 0.88 | UPP1 (0.54) | RNASE1UPP1TK2TK1 | |
| SCHEMBL9811657 | 0.87 | UPP1 (0.52) | RNASE1UPP1 | |
| SCHEMBL9228356 | 0.86 | LMNA (0.52) | RNASE1UPP1TK2 | |
| SCHEMBL9228359 | 0.86 | LMNA (0.52) | RNASE1UPP1TK2 | |
| SCHEMBL6926181 | 0.84 | TK1 (0.53) | RNASE1UPP1TK2TK1 | |
| SCHEMBL6235590 | 0.84 | TK1 (0.53) | RNASE1UPP1TK2TK1 | |
| SCHEMBL5709922 | 0.84 | UPP1 (0.57) | RNASE1UPP1 | |
| SCHEMBL30698170 | 0.81 | RNASE1 (0.61) | RNASE1UPP1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363928-B1 | PROCESS FOR THE PREPARATION OF (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE | MENARINI RICERCHE SPA (IT) | 2005-05-04 | — | — | EP | disclosed |
| US-6864366-B2 | Process for the preparation of (e)-5-(2-bromovinyl)-2′-deoxyuridine | MENARINI RICHERCHE S.P.A. (IT) | 2005-03-08 | — | — | US | disclosed |
| US-20040077586-A1 | Process for the preparation of (e)-5-(2-bromovinyl)-2'-deoxyuridine | MENARINI RICERCHE S.P.A. (IT) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077586-A1 | Process for the preparation of (e)-5-(2-bromovinyl)-2'-deoxyuridine | DUT, DUS2, DPYD | RNASE1 1417/4885UPP1 41/4885TK2 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.