SCHEMBL5710084

SCHEMBL5710084

COc1ccc(-c2cc(-c3ccc(N(C)C)cc3)cc(-c3ccc(OC)cc3)n2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
MAPT P10636 2/20 0.55
HPGD P15428 1/20 0.55
HSD17B10 Q99714 1/20 0.55
APP P05067 5/20 0.55
PTGDR Q13258 1/20 0.53
TLR9 Q9NR96 1/20 0.52
TLR7 Q9NYK1 1/20 0.52
ADORA3 P0DMS8 1/20 0.51
AURKA O14965 1/20 0.51
SLC2A1 P11166 1/20 0.50
GLA P06280 1/20 0.50
GAA P10253 1/20 0.50
MCL1 Q07820 2/20 0.49
DYRK1A Q13627 1/20 0.49
ACHE P22303 1/20 0.48
ACP1 P24666 1/20 0.46
PDGFRB P09619 1/20 0.46
PDGFRA P16234 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8616869 1.00 KDM4E (0.55) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL7859483 0.88 ADORA3 (0.61) KDM4EALDH1A1MAPTHPGDADORA3
SCHEMBL8618775 0.88 MAPT (0.54) KDM4EALDH1A1MAPTHSD17B10APP
SCHEMBL10974850 0.84 ACP1 (0.51) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL11714214 0.84 APP (0.71) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL28979784 0.83 DYRK1A (0.55) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL8202172 0.83 MCL1 (0.54) KDM4EALDH1A1MAPTHPGDADORA3
SCHEMBL14801186 0.83 MAPT (0.56) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL8621142 0.83 MAPT (0.56) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL8621740 0.82 ADORA3 (0.49) KDM4EALDH1A1MAPTHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
EP-1179435-B1 Reversible thermochromic composition having improved light-fastness and product comprising same PILOT INK CO LTD (JP) 2006-11-29 EP disclosed
US-6638620-B2 Discoloration sensitivity THE PILOT INK CO., LTD. (JP) 2003-10-28 US disclosed
EP-1179435-A1 Reversible thermochromic composition having improved light-fastness and product comprising same The Pilot Ink Co., Ltd. (JP) 2002-02-13 EP disclosed
EP-0659582-B1 Reversible thermochromic composition PILOT INK CO LTD (JP) 1998-05-13 EP disclosed
EP-0665119-B1 Thermochromic colour-memory composition PILOT INK CO LTD (JP) 1997-12-03 EP disclosed
US-5558700-A QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
US-5558699-A COLOR IS RETAINED AFTER HEATING OR COOLING IS WITHDRAWN, REACTION MEDIUM IS ALKYL OR ALKYLARYL KETONE THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
EP-0665119-A1 Thermochromic colour-memory composition THE PILOT INK CO., LTD. (JP) 1995-08-02 EP disclosed
EP-0659582-A1 Reversible thermochromic composition THE PILOT INK CO., LTD. (JP) 1995-06-28 EP disclosed
US-4600678-A CHROMOGENS, PHOTOINITIATORS, FREE RADICAL ADDITION POLYMERIZABLE MATERIAL THE MEAD CORPORATION (US) 1986-07-15 US disclosed