SCHEMBL5710144

SCHEMBL5710144

C=C(C)C(=O)OCC(C)C.C=CC(=O)OC1CC2CCC1(C)C2(C)C.C=CC(=O)OCC(CC)CCCC

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
CYP2C19 P33261 1/20 0.36
ELANE P08246 2/20 0.35
HTT P42858 4/20 0.35
LMNA P02545 4/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
PLA2G1B P04054 1/20 0.34
MAPK1 P28482 1/20 0.34
RAD52 P43351 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3631701 0.95 TSHR (0.47) TSHRCYP2C19ELANEHTTLMNA
SCHEMBL3631698 0.95 TSHR (0.47) TSHRCYP2C19ELANEHTTLMNA
SCHEMBL5710094 0.93 TSHR (0.51) TSHRCYP2C19ELANEHTTLMNA
SCHEMBL645585 0.90 TSHR (0.43) TSHRCYP2C19ELANEHTTLMNA
SCHEMBL28073424 0.87 LMNA (0.41) TSHRHTTLMNAMEN1KMT2A
SCHEMBL646900 0.86 TSHR (0.43) TSHRCYP2C19ELANEHTTLMNA
SCHEMBL645426 0.86 TSHR (0.43) TSHRCYP2C19ELANEHTTLMNA
SCHEMBL916115 0.84 TSHR (0.45) TSHRCYP2C19ELANEHTTLMNA
Acrylic Acid SCHEMBL4888290 0.83 CYP2C19 (0.43) TSHRCYP2C19ELANEHTTLMNA
SCHEMBL644917 0.83 HTT (0.44) TSHRCYP2C19ELANEHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210055-B1 TWO-CONSTITUENT ELASTOMER MATERIALS BASED ON ALKYL AZIRIDINE COMPRISING A CATALYST CONSTITUENT THAT CONTAINS A BORIC ACID COMPLEX 3M ESPE AG (DE) 2006-11-22 EP disclosed
EP-1163281-B1 TWO-COMPONENT PREPARATIONS CONTAINING EPOXY COMPOUNDS 3M ESPE AG (DE) 2005-01-05 EP disclosed
EP-1210055-A1 TWO-CONSTITUENT ELASTOMER MATERIALS BASED ON ALKYL AZIRIDINE COMPRISING A CATALYST CONSTITUENT THAT CONTAINS A BORIC ACID COMPLEX 3M Espe AG (DE) 2002-06-05 EP disclosed
EP-1163281-A1 TWO-COMPONENT PREPARATIONS CONTAINING EPOXY COMPOUNDS 3M Espe AG (DE) 2001-12-19 EP disclosed
WO-2001017483-A1 TWO-CONSTITUENT ELASTOMER MATERIALS BASED ON ALKYL AZIRIDINE COMPRISING A CATALYST CONSTITUENT THAT CONTAINS A BORIC ACID COMPLEX 3M ESPE AG (DE) 2001-03-15 WO disclosed
WO-2000056800-A1 TWO-COMPONENT PREPARATIONS CONTAINING EPOXY COMPOUNDS 3M ESPE AG (DE) 2000-09-28 WO disclosed