SCHEMBL916115

SCHEMBL916115

C=C(C)C(=O)OC1CC2CCC1(C)C2(C)C.C=C(C)C(=O)OC1CC2CCC1(C)C2(C)C.C=CC(=O)OCC(C)C

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
ELANE P08246 1/20 0.41
KMT2A Q03164 2/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
CYP19A1 P11511 2/20 0.40
MEN1 O00255 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL646900 0.98 TSHR (0.43) TSHRCYP2C19ALDH1A1LMNAELANE
SCHEMBL645426 0.98 TSHR (0.43) TSHRCYP2C19ALDH1A1LMNAELANE
Acrylic Acid SCHEMBL15775512 0.97 CYP2C19 (0.42) TSHRCYP2C19ALDH1A1LMNAELANE
Acrylic Acid SCHEMBL4888290 0.95 CYP2C19 (0.43) TSHRCYP2C19ALDH1A1LMNAELANE
SCHEMBL645585 0.94 TSHR (0.43) TSHRCYP2C19ALDH1A1LMNAELANE
SCHEMBL14842784 0.90 TSHR (0.50) TSHRALDH1A1LMNAKMT2AMAPT
SCHEMBL4940905 0.90 TSHR (0.50) TSHRALDH1A1LMNAKMT2AMAPT
Acrylic Acid Ethyl Ester SCHEMBL28834563 0.88 KMT2A (0.44) CYP2C19ALDH1A1LMNAELANEKMT2A
SCHEMBL1684006 0.87 TSHR (0.39) TSHRCYP2C19ALDH1A1LMNAELANE
SCHEMBL1079138 0.87 CYP2C19 (0.42) TSHRCYP2C19ALDH1A1LMNAELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7875265-B2 A cosmetic composition comprising a specific block polymer and a specific plasticizer intended to be applied to human keratinous substances, such as the skin, lips, eyelashes, eyebrows, nails or hair; film-forming acrylic polymers containing a plasticizer; flexibility; good hold; transfer-free L'OREAL (FR) 2011-01-25 US disclosed
US-20060147403-A1 Non-transfer cosmetic composition comprising a sequenced polymer L'OREAL C.A. 2006-07-06 US disclosed
US-20060134044-A1 Cosmetic composition comprising a sequenced polymer and a plasticizer L'OREAL (FR) 2006-06-22 US disclosed
US-20060127334-A1 Lipstick comprising a sequenced polymer L'OREAL S.A. (FR) 2006-06-15 US disclosed
CN-1504488-A Block copolymers and cosmetic compositions containing such polymers �ź㴫 2004-06-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060147403-A1 Non-transfer cosmetic composition comprising a sequenced polymer KRT18, CUTA, LMNB2 TSHR 4399/4885CYP2C19 3727/4885ALDH1A1 3889/4885
US-20060134044-A1 Cosmetic composition comprising a sequenced polymer and a plasticizer NFKB1, NFKB2, POLL TSHR 3325/4885CYP2C19 3531/4885ALDH1A1 2665/4885
US-20060127334-A1 Lipstick comprising a sequenced polymer LIPC, LIPA, LARP7 TSHR 4549/4885CYP2C19 3015/4885ALDH1A1 4454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.