SCHEMBL645585

SCHEMBL645585

C=C(C)C(=O)OCC(C)C.C=CC(=O)OC1CC2CCC1(C)C2(C)C.C=CC(=O)OCC(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
CYP2C19 P33261 1/20 0.43
ELANE P08246 2/20 0.41
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
GAA P10253 1/20 0.39
APOBEC3A P31941 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL646900 0.96 TSHR (0.43) TSHRCYP2C19ELANEALDH1A1LMNA
SCHEMBL645426 0.96 TSHR (0.43) TSHRCYP2C19ELANEALDH1A1LMNA
SCHEMBL916115 0.94 TSHR (0.45) TSHRCYP2C19ELANEALDH1A1LMNA
Acrylic Acid SCHEMBL4888290 0.93 CYP2C19 (0.43) TSHRCYP2C19ELANEALDH1A1LMNA
Acrylic Acid SCHEMBL15775512 0.91 CYP2C19 (0.42) TSHRCYP2C19ELANEALDH1A1LMNA
SCHEMBL5710144 0.90 TSHR (0.47) TSHRCYP2C19ELANEALDH1A1LMNA
SCHEMBL4940905 0.88 TSHR (0.50) TSHRALDH1A1LMNAKMT2AMAPT
SCHEMBL14842784 0.88 TSHR (0.50) TSHRALDH1A1LMNAKMT2AMAPT
SCHEMBL1079138 0.87 CYP2C19 (0.42) TSHRCYP2C19ELANEALDH1A1LMNA
SCHEMBL17054726 0.86 CYP2C19 (0.47) CYP2C19ELANEALDH1A1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7932324-B2 Block polymers and cosmetic compositions and processes comprising them L'OREAL (FR) 2011-04-26 US claimed
US-20080014235-A1 Novel Block Polymers and Cosmetic Compositions and Processes Comprising Them L'OREAL 2008-01-17 US claimed
US-20070166259-A1 Cosmetic composition comprising a tensioning agent and a particular block ethylenic polymer L'OREAL (FR) 2007-07-19 US claimed
EP-1675558-A1 COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A PARTICULAR BLOCK ETHYLENIC POLYMER L'OREAL (FR) 2006-07-05 EP claimed
WO-2005030158-A1 COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A PARTICULAR BLOCK ETHYLENIC POLYMER L'OREAL (FR) 2005-04-07 WO claimed
US-20040120920-A1 Novel block polymers and cosmetic compositions and processes comprising them L'OREAL S.A. (FR) 2004-06-24 US claimed
WO-2023118526-A1 COSMETIC COMPOSITION COMPRISING A POLYHYDROXYALKANOATE COPOLYMER BEARING A (UN)SATURATED HYDROCARBON-BASED CHAIN AND A HYDROCARBON-BASED POLYMER L'OREAL (FR) 2023-06-29 WO disclosed
CN-107743392-B Oil-in-water emulsion composition 莱雅公司 2021-05-07 CN disclosed
EP-3341083-B1 OIL-IN-WATER EMULSION COMPOSITION OREAL (FR) 2021-03-24 EP disclosed
EP-1579845-B1 Cosmetic composition comprising a polyglycerolated silicone elastomer L'ORÉAL (FR) 2017-04-19 EP disclosed
EP-2079437-B1 PROCESS FOR MAKING UP KERATIN FIBRES AND PACKAGING ASSEMBLY ORÉAL L (FR) 2016-08-17 EP disclosed
US-9017704-B2 Composition comprising a block polymer and a film-forming agent L'OREAL (FR) 2015-04-28 US disclosed
US-8992903-B2 Composition comprising at least one block polymer and at least one gelling agent L'OREAL (FR) 2015-03-31 US disclosed
WO-2005058274-A1 COMPOSITION COMPRISING A DISPERSION OF PARTICLES OF A GRAFTED ETHYLENIC POLYMER AND A FILM-FORMING AGENT L'ORÉAL (FR) 2005-06-30 WO disclosed
US-20050106197-A1 Cosmetic composition comprising a block polymer and a non-volatile silicone oil L'OREAL S.A. (FR) 2005-05-19 US disclosed
US-20050095213-A1 Two-coat cosmetic product, cosmetic process of using thereof and makeup kit containing this product L'OREAL S.A. (FR) 2005-05-05 US disclosed
WO-2005030155-A1 CONTINUOUS AQUEOUS PHASE-BASED PHOTOPROTECTIVE COMPOSITION CONTAINING A POLYMER COMPRISING AT LEAST TWO BLOCKS INCOMPATIBLE WITH EACH OTHER AND HAVING DIFFERENT GLASS TRANSITION TEMPERATURES L'ORÉAL (FR) 2005-04-07 WO disclosed
WO-2005030158-A1 COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A PARTICULAR BLOCK ETHYLENIC POLYMER L'OREAL (FR) 2005-04-07 WO disclosed
EP-1518534-A2 Bilayered cosmetic product, uses thereof and kit-of-parts containing this product. L'OREAL (FR) 2005-03-30 EP disclosed
US-20040120920-A1 Novel block polymers and cosmetic compositions and processes comprising them L'OREAL S.A. (FR) 2004-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080014235-A1 Novel Block Polymers and Cosmetic Compositions and Processes Comprising Them FANCI, GDI2, TBCB TSHR 2647/4885CYP2C19 2716/4885ELANE 3403/4885
US-20050095213-A1 Two-coat cosmetic product, cosmetic process of using thereof and makeup kit containing this product CUTA, PRKACB, PRKDC TSHR 4235/4885CYP2C19 4071/4885ELANE 1106/4885
US-20040120920-A1 Novel block polymers and cosmetic compositions and processes comprising them FANCI, GDI2, TBCB TSHR 2647/4885CYP2C19 2716/4885ELANE 3403/4885
US-20070166259-A1 Cosmetic composition comprising a tensioning agent and a particular block ethylenic polymer CUTA, ERCC1, RAD23B TSHR 4004/4885CYP2C19 2779/4885ELANE 483/4885
US-20050106197-A1 Cosmetic composition comprising a block polymer and a non-volatile silicone oil KRT18, CUTA, DSG1 TSHR 3624/4885CYP2C19 3005/4885ELANE 532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.