Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279823 | 0.90 | KDM4E (0.56) | GRM5KDM4EHSD17B10P2RX7ALDH1A1 | |
| SCHEMBL28278292 | 0.89 | GABRA1 (0.45) | GRM5KDM4EHSD17B10P2RX7MAPT | |
| SCHEMBL28434913 | 0.89 | RAB9A (0.48) | GRM5KDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL186881 | 0.86 | KDM4E (0.51) | GRM5KDM4EHSD17B10P2RX7ALDH1A1 | |
| SCHEMBL28741853 | 0.82 | GRM5 (0.39) | GRM5KDM4EHSD17B10P2RX7 | |
| SCHEMBL29626720 | 0.82 | FYN (0.45) | GRM5ALDH1A1MAPTKMT2ARAB9A | |
| SCHEMBL28741803 | 0.82 | FYN (0.45) | GRM5ALDH1A1MAPTKMT2ARAB9A | |
| SCHEMBL29640089 | 0.82 | GRM5 (0.39) | GRM5KDM4EHSD17B10P2RX7 | |
| SCHEMBL27750896 | 0.81 | GRM5 (0.41) | GRM5KDM4EHSD17B10P2RX7ALDH1A1 | |
| SCHEMBL28823612 | 0.79 | KDM4E (0.49) | GRM5KDM4EHSD17B10P2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727397-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2006-11-29 | — | — | EP | disclosed |