Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 2/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 3/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452371 | 0.82 | KDM1A (0.48) | P2RY14KDM1ANAMPTRIPK1TLR9 | |
| SCHEMBL8414100 | 0.82 | P2RY14 (0.47) | P2RY14KDM1ANAMPTRIPK1TLR9 | |
| SCHEMBL20705482 | 0.82 | RAB9A (0.50) | P2RY14KDM1ANAMPTTLR9TLR8 | |
| SCHEMBL571141 | 0.81 | KDM1A (0.60) | P2RY14KDM1ARIPK1RBP4NPC1 | |
| SCHEMBL19371919 | 0.81 | NPC1 (0.44) | NAMPTQDPRNPC1MAPTHPGD | |
| SCHEMBL15254117 | 0.81 | P2RY14 (0.56) | P2RY14KDM1ANAMPTRIPK1TLR9 | |
| SCHEMBL20124850 | 0.79 | P2RY14 (0.45) | P2RY14KDM1ANAMPTRIPK1TLR9 | |
| SCHEMBL571736 | 0.79 | P2RY14 (0.47) | P2RY14KDM1ANAMPTRIPK1TLR9 | |
| SCHEMBL6126281 | 0.79 | P2RY14 (0.45) | P2RY14KDM1ANAMPTRIPK1TLR9 | |
| SCHEMBL10243175 | 0.79 | MAPT (0.50) | P2RY14KDM1ANAMPTRIPK1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12319683-B2 | Azabenzimidazole compounds and pharmaceutical | NIPPON SHINYAKU CO., LTD. (JP) | 2025-06-03 | — | — | US | disclosed |
| EP-3792260-B1 | AZABENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL | NIPPON SHINYAKU CO LTD (JP) | 2024-09-11 | — | — | EP | disclosed |
| CN-112368282-B | Azabenzimidazole compounds and medicaments | 日本新药株式会社 | 2023-10-13 | — | — | CN | disclosed |
| US-20210371412-A1 | AZABENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL | NIPPON SHINYAKU CO., LTD. (JP) | 2021-12-02 | — | — | US | disclosed |
| EP-3792260-A1 | AZABENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL | Nippon Shinyaku Co., Ltd. (JP) | 2021-03-17 | — | — | EP | disclosed |
| CN-112368282-A | Azabenzimidazole compounds and pharmaceuticals | 日本新药株式会社 | 2021-02-12 | — | — | CN | disclosed |
| US-10196373-B2 | Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT protein | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2019-02-05 | — | — | US | disclosed |
| US-10196373-B2 | Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT protein | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2019-02-05 | — | — | US | disclosed |
| EP-2900643-B1 | QUINAZOLINONE DERIVATIVES AS PARP INHIBITORS | MERCK PATENT GMBH (DE) | 2017-09-27 | — | — | EP | disclosed |
| US-9388142-B2 | Quinazolinone derivatives as PARP inhibitors | MERCK PATENT GMBH (DE) | 2016-07-12 | — | — | US | disclosed |
| EP-2640724-A1 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-09-25 | — | — | EP | disclosed |
| US-20130225621-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEIN | UNIVERSITY OF TORONTO MISSISSAUGA (CA) | 2013-08-29 | — | — | US | disclosed |
| US-20130225621-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEIN | UNIVERSITY OF TORONTO MISSISSAUGA (CA) | 2013-08-29 | — | — | US | disclosed |
| EP-2600860-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEINS | University of Central Florida Research Foundation, Inc. (US) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012066234-A9 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012066234-A1 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-05-24 | — | — | WO | disclosed |
| WO-2012018868-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEINS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-02-09 | — | — | WO | disclosed |
| WO-2012018868-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEINS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-02-09 | — | — | WO | disclosed |
| CN-1094035-A | Carboxylic acid derivative contains pharmaceutical composition of these compounds and preparation method thereof | THOMAE GMBH DR K (DE) | 1994-10-26 | — | — | CN | disclosed |
| EP-0604800-A1 | 4- 4- 4-(carboxyalkyl)-phenyl amino carbonyl -phenyl -piperedines as aggregation inhibitors | Dr. Karl Thomae GmbH (DE) | 1994-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371412-A1 | AZABENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL | PAM, CHRM3, AZI2 | P2RY14 65/4885KDM1A 558/4885NAMPT 512/4885 |
| US-20130225621-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEIN | STAT3, STAT1, STAT4 | P2RY14 3048/4885KDM1A 2433/4885NAMPT 2249/4885 |
| US-10196373-B2 | Substituted 2-hydroxy-4-(2-(phenylsulfonamido)acetamido)benzoic acid analogs as inhibitors of STAT protein | STAT3, STAT1, STAT4 | P2RY14 3048/4885KDM1A 2433/4885NAMPT 2249/4885 |
| US-12319683-B2 | Azabenzimidazole compounds and pharmaceutical | PAM, CHRM3, AZI2 | P2RY14 65/4885KDM1A 558/4885NAMPT 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.