Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MET | P08581 | 10/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711099 | 0.91 | MET (0.48) | RAB9AMETKITPDGFRAKDR | |
| SCHEMBL9958089 | 0.89 | MET (0.60) | METPDGFRAKDR | |
| SCHEMBL4332082 | 0.83 | MET (0.56) | RAB9AMETKITPDGFRAKDR | |
| SCHEMBL4332073 | 0.82 | MET (0.54) | RAB9AMETKITPDGFRAKDR | |
| SCHEMBL6031858 | 0.79 | MET (0.60) | METPDGFRAKDR | |
| SCHEMBL13861029 | 0.77 | MET (0.52) | RAB9AMETKITPDGFRAKDR | |
| SCHEMBL9958107 | 0.77 | MEN1 (0.51) | RAB9AMETKITPDGFRAKDR | |
| SCHEMBL9957603 | 0.77 | MEN1 (0.51) | RAB9AMETKITPDGFRAALDH1A1 | |
| SCHEMBL13861023 | 0.75 | MET (0.54) | RAB9AMETKITPDGFRAKDR | |
| SCHEMBL5711096 | 0.75 | MET (0.45) | RAB9AMETALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719762-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | disclosed |
| EP-1719763-A1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (2) | Eisai Co., Ltd. (JP) | 2006-11-08 | — | — | EP | disclosed |