Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.60 |
| ▸ | KDR | P35968 | 18/20 | 0.60 |
| ▸ | AXL | P30530 | 2/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031858 | 0.91 | MET (0.60) | METKDRPDGFRBPDGFRA | |
| SCHEMBL5711073 | 0.89 | RAB9A (0.52) | METKDRPDGFRA | |
| SCHEMBL9958254 | 0.84 | MET (0.59) | METKDRAXLPDGFRBPDGFRA | |
| SCHEMBL4322995 | 0.83 | MET (0.71) | METKDR | |
| SCHEMBL9958107 | 0.82 | MEN1 (0.51) | METKDRPDGFRA | |
| SCHEMBL4322992 | 0.82 | MET (0.66) | METKDRAXLPDGFRBPDGFRA | |
| SCHEMBL27704510 | 0.81 | POLB (0.47) | MET | |
| SCHEMBL4340635 | 0.80 | MET (0.60) | METKDRAXLPDGFRBPDGFRA | |
| SCHEMBL5711099 | 0.79 | MET (0.48) | METKDRPDGFRBPDGFRA | |
| SCHEMBL4330760 | 0.78 | MET (0.58) | METKDRAXLPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719762-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | claimed |
| EP-1719762-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | disclosed |