Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9957603 | 0.91 | MEN1 (0.51) | KMT2AMEN1METGAANPC1 | |
| SCHEMBL5711096 | 0.88 | MET (0.45) | KMT2AMEN1METPOLBGAA | |
| SCHEMBL9958429 | 0.88 | MET (0.58) | KMT2AMEN1METCA1CA2 | |
| SCHEMBL4335620 | 0.83 | MET (0.53) | KMT2AMEN1METCA1CA2 | |
| SCHEMBL4335613 | 0.81 | MET (0.49) | KMT2AMEN1METCA1CA2 | |
| SCHEMBL9958107 | 0.80 | MEN1 (0.51) | KMT2AMEN1METGAARAB9A | |
| SCHEMBL5711099 | 0.77 | MET (0.48) | KMT2AMEN1METPOLBNPC1 | |
| SCHEMBL6031858 | 0.77 | MET (0.60) | MET | |
| SCHEMBL13861047 | 0.76 | FAAH (0.46) | KMT2AMEN1MET | |
| SCHEMBL4328418 | 0.74 | MEN1 (0.52) | KMT2AMEN1METCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719763-A1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (2) | Eisai Co., Ltd. (JP) | 2006-11-08 | — | — | EP | disclosed |