Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14688027 | 0.97 | FDPS (0.43) | FDPSBLMTDP1LMNA | |
| SCHEMBL4823622 | 0.86 | FDPS (0.38) | FDPSBLMTDP1BTN3A1 | |
| Hydroquinone SCHEMBL20496395 | 0.85 | KDM4E (0.46) | FDPSBLMTDP1LMNA | |
| SCHEMBL2871050 | 0.83 | — | — | |
| Tetrabuthylammonium SCHEMBL28999739 | 0.81 | SMPD1 (0.42) | FDPS | |
| SCHEMBL2871051 | 0.79 | FDPS (0.45) | FDPSBLMTDP1LMNABTN3A1 | |
| SCHEMBL27570533 | 0.77 | LMNA (0.40) | FDPSBLMTDP1LMNA | |
| SCHEMBL332472 | 0.77 | — | — | |
| SCHEMBL28697608 | 0.77 | FDPS (0.33) | FDPSBLMTDP1BTN3A1 | |
| SCHEMBL486485 | 0.76 | TSHR (0.31) | TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367482-A | N-acylsulfamide apoptosis accelerator | ASTRAZENECA AB | 2016-03-02 | — | — | CN | disclosed |
| CN-103153954-B | N-acylsulfonamide apoptosis promoters | ASTRAZENECA AB (SE) | 2015-11-25 | — | — | CN | disclosed |
| EP-2601177-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | AstraZeneca AB (SE) | 2013-06-12 | — | — | EP | disclosed |
| CN-103153954-A | N-acylsulfonamide apoptosis promoters | ASTRAZENECA AB | 2013-06-12 | — | — | CN | disclosed |
| WO-2012017251-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ASTRAZENECA AB (SE) | 2012-02-09 | — | — | WO | disclosed |
| CN-1390234-A | Amine-containing graft polymers, a method for making same, and their use | EXXON CHEMICAL PATENTS INC (US) | 2003-01-08 | — | — | CN | disclosed |