Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | CCR1 | P32246 | 6/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711242 | 0.89 | CCR1 (0.50) | ACECCR1 | |
| SCHEMBL5711206 | 0.85 | CMA1 (0.51) | ACECCR1CMA1 | |
| SCHEMBL7660638 | 0.84 | CCR1 (0.46) | ACECCR1CMA1PIN1XIAP | |
| SCHEMBL5711229 | 0.82 | CAPN1 (0.58) | ACECCR1 | |
| SCHEMBL7665844 | 0.82 | ACE (0.47) | ACEAGTR2 | |
| SCHEMBL18619614 | 0.82 | ACE (0.59) | ACECCR1CMA1 | |
| SCHEMBL20484547 | 0.82 | ACE (0.59) | ACECCR1CMA1 | |
| SCHEMBL7372924 | 0.81 | SMN1; SMN2 (0.46) | CCR1PIN1XIAP | |
| SCHEMBL7664524 | 0.78 | CCR1 (0.52) | CCR1AGTR2 | |
| SCHEMBL5711285 | 0.78 | CCR1 (0.50) | ACECCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |