Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 13/20 | 0.51 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 3/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711265 | 0.91 | ELANE (0.43) | CMA1CCR1ELANECTSG | |
| SCHEMBL5711224 | 0.89 | CMA1 (0.48) | CMA1ELANECTSGACE | |
| SCHEMBL5711388 | 0.89 | CMA1 (0.43) | CMA1ELANECTSG | |
| SCHEMBL7665223 | 0.87 | CMA1 (0.42) | CMA1ELANECTSG | |
| SCHEMBL7660638 | 0.85 | CCR1 (0.46) | CMA1CCR1ELANEACE | |
| SCHEMBL5711172 | 0.85 | TACR1 (0.47) | CMA1ELANECTSG | |
| SCHEMBL7666940 | 0.85 | CAPN1 (0.50) | CMA1CCR1 | |
| SCHEMBL5711319 | 0.85 | CAPN1 (0.50) | CMA1CCR1 | |
| SCHEMBL5711237 | 0.85 | ELANE (0.49) | CMA1ELANE | |
| SCHEMBL5711235 | 0.85 | ACE (0.52) | CMA1CCR1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1103560-A1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-05-30 | — | — | EP | disclosed |