Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.58 |
| ▸ | CTSB | P07858 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667089 | 0.91 | CTSL (0.53) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL7667094 | 0.91 | CTSL (0.53) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL5711277 | 0.90 | CAPN1 (0.48) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL5711352 | 0.89 | PREP (0.57) | CAPN1CTSBCTSKCTSLACE | |
| SCHEMBL5711367 | 0.87 | ACE (0.48) | CAPN1ACEDPP4PREPCASP1 | |
| SCHEMBL5711384 | 0.86 | CTSK (0.55) | CTSBCTSKCTSLDPP4CTSS | |
| SCHEMBL5711341 | 0.85 | DPP4 (0.55) | CTSKCTSLACEDPP4PREP | |
| SCHEMBL5711319 | 0.85 | CAPN1 (0.50) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL7666940 | 0.85 | CAPN1 (0.50) | CAPN1CTSBCTSKCTSLCCR1 | |
| SCHEMBL7668192 | 0.85 | CAPN1 (0.49) | CAPN1CTSBCTSKCTSLCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |