Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 12/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711229 | 0.84 | CAPN1 (0.58) | CCR1ACECAPN1 | |
| SCHEMBL5711242 | 0.82 | CCR1 (0.50) | CCR1ACECAPN1 | |
| SCHEMBL5711237 | 0.82 | ELANE (0.49) | ELANE | |
| SCHEMBL7664392 | 0.81 | ELANE (0.47) | CCR1ELANE | |
| SCHEMBL5711416 | 0.79 | PREP (0.51) | ELANEACE | |
| SCHEMBL7963876 | 0.79 | PREP (0.51) | ELANEACE | |
| SCHEMBL5711277 | 0.79 | CAPN1 (0.48) | CCR1ACECAPN1 | |
| SCHEMBL5711235 | 0.78 | ACE (0.52) | CCR1ACE | |
| SCHEMBL5711178 | 0.78 | ACE (0.56) | CCR1ACE | |
| SCHEMBL7665844 | 0.78 | ACE (0.47) | ACECAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |