SCHEMBL5711237

SCHEMBL5711237

CC(C)[C@H](NC(=O)Oc1ccccc1)C(=O)N1CSC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 9/20 0.49
CMA1 P23946 11/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7666940 0.90 CAPN1 (0.50) CMA1
SCHEMBL5711319 0.90 CAPN1 (0.50) CMA1
SCHEMBL5711366 0.89 CMA1 (0.58) CMA1
SCHEMBL5711265 0.89 ELANE (0.43) ELANECMA1
SCHEMBL5711224 0.88 CMA1 (0.48) ELANECMA1
SCHEMBL7665223 0.88 CMA1 (0.42) ELANECMA1
SCHEMBL7665098 0.86 CMA1 (0.46) CMA1
SCHEMBL5711388 0.86 CMA1 (0.43) ELANECMA1
SCHEMBL7664392 0.85 ELANE (0.47) ELANECMA1
SCHEMBL5711206 0.85 CMA1 (0.51) ELANECMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1103560-B1 NOVEL THIAZOLIDINE DERIVATIVES SANTEN PHARMACEUTICAL CO LTD (JP) 2006-12-27 EP disclosed
US-6410576-B1 ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS SANTEN PHARMACEUTICAL CO., LTD. (JP) 2002-06-25 US disclosed
EP-1103560-A1 NOVEL THIAZOLIDINE DERIVATIVES SANTEN PHARMACEUTICAL CO., LTD. (JP) 2001-05-30 EP disclosed