Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 10/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711388 | 0.92 | CMA1 (0.43) | CMA1ELANECTSGPSMB5 | |
| SCHEMBL5711265 | 0.91 | ELANE (0.43) | CMA1ELANECTSG | |
| SCHEMBL5711237 | 0.88 | ELANE (0.49) | CMA1ELANE | |
| SCHEMBL5711206 | 0.87 | CMA1 (0.51) | CMA1ELANECTSG | |
| SCHEMBL5711224 | 0.87 | CMA1 (0.48) | CMA1ELANECTSG | |
| SCHEMBL7655849 | 0.86 | CTSD (0.46) | PSMB5 | |
| SCHEMBL7666940 | 0.85 | CAPN1 (0.50) | CMA1CTSLALDH1A1 | |
| SCHEMBL5711319 | 0.85 | CAPN1 (0.50) | CMA1CTSLALDH1A1 | |
| SCHEMBL5711366 | 0.84 | CMA1 (0.58) | CMA1MEN1KMT2A | |
| SCHEMBL5711172 | 0.83 | TACR1 (0.47) | CMA1ELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1103560-A1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-05-30 | — | — | EP | disclosed |