Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CMA1 | P23946 | 13/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711206 | 0.91 | CMA1 (0.51) | ELANECTSGCCR1CMA1 | |
| SCHEMBL5711224 | 0.91 | CMA1 (0.48) | ELANECTSGCMA1CAPN1 | |
| SCHEMBL7665223 | 0.91 | CMA1 (0.42) | ELANECTSGCMA1 | |
| SCHEMBL5711388 | 0.90 | CMA1 (0.43) | ELANECTSGCMA1 | |
| SCHEMBL5711237 | 0.89 | ELANE (0.49) | ELANECMA1 | |
| SCHEMBL5711172 | 0.87 | TACR1 (0.47) | ELANECTSGCMA1 | |
| SCHEMBL7666940 | 0.87 | CAPN1 (0.50) | CCR1CMA1CAPN1 | |
| SCHEMBL5711319 | 0.87 | CAPN1 (0.50) | CCR1CMA1CAPN1 | |
| SCHEMBL5711366 | 0.86 | CMA1 (0.58) | CMA1 | |
| SCHEMBL5711177 | 0.86 | ELANE (0.43) | ELANECTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| EP-1103560-A1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-05-30 | — | — | EP | disclosed |