Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.51 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869086 | 0.84 | LMNA (0.55) | NOTUMHTTKDM4ESMN1; SMN2CES1 | |
| SCHEMBL1048074 | 0.82 | NOTUM (1.00) | NOTUMHTTKDM4ECES1KCNN4 | |
| SCHEMBL30003296 | 0.82 | NOTUM (1.00) | NOTUMHTTKDM4ECES1KCNN4 | |
| SCHEMBL7003872 | 0.79 | NOTUM (0.73) | NOTUMHTTKDM4ESMN1; SMN2CES1 | |
| SCHEMBL25139324 | 0.77 | KDM4E (0.59) | NOTUMHTTKDM4ESMN1; SMN2CES1 | |
| SCHEMBL22652710 | 0.76 | KDM4E (0.58) | NOTUMHTTKDM4ESMN1; SMN2CES1 | |
| SCHEMBL9537965 | 0.76 | CES1 (0.48) | NOTUMHTTKDM4ESMN1; SMN2CES1 | |
| SCHEMBL9537973 | 0.76 | CES1 (0.48) | NOTUMHTTKDM4ESMN1; SMN2CES1 | |
| SCHEMBL24455243 | 0.75 | KDM4E (0.57) | NOTUMHTTKDM4ESMN1; SMN2CES1 | |
| SCHEMBL68111 | 0.75 | KCNN4 (0.68) | NOTUMHTTKCNN4KCNA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432428-B1 | Agent for colouring fibres containing keratin | HENKEL KGAA (DE) | 2006-11-02 | — | — | EP | claimed |
| EP-1432428-A1 | Agent for colouring fibres containing keratin | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| WO-2003030842-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-1432428-B1 | Agent for colouring fibres containing keratin | HENKEL KGAA (DE) | 2006-11-02 | — | — | EP | disclosed |
| EP-1432428-A1 | Agent for colouring fibres containing keratin | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003030842-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | disclosed |