Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | PTPRA | P18433 | 1/20 | 0.55 |
| ▸ | PTPRB | P23467 | 1/20 | 0.55 |
| ▸ | PTPRE | P23469 | 1/20 | 0.55 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.55 |
| ▸ | KDM6B | O15054 | 2/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356043 | 0.89 | PLK1 (0.53) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL3898806 | 0.88 | PTPRC (0.60) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL15636019 | 0.83 | PTGER4 (0.55) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL17938288 | 0.82 | HCAR3 (0.62) | KDM6BKDM4CCISD1APEX1HCAR3 | |
| SCHEMBL15635660 | 0.81 | APEX1 (0.72) | KDM6BKDM4CCISD1APEX1HCAR3 | |
| SCHEMBL8991944 | 0.81 | KDM6B (0.51) | KDM6BKDM4CCISD1APEX1HCAR3 | |
| SCHEMBL15639856 | 0.81 | KDM4E (0.59) | KDM6BKDM4CCISD1APEX1HCAR3 | |
| SCHEMBL14075416 | 0.78 | PLK1 (0.62) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL2384775 | 0.78 | PTPRC (0.64) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL3888815 | 0.77 | LIPC (0.63) | KDM6BKDM4CCISD1APEX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1344775-B1 | Preparation of fungicidal quinazolinones and useful intermediates | DU PONT (US) | 2006-11-29 | — | — | EP | disclosed |
| EP-1344775-A1 | Preparation of fungicidal quinazolinones and useful intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-17 | — | — | EP | disclosed |
| US-6166208-A | Preparation of fungicidal quinazolinones and useful intermediates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0922037-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1997048684-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |