Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491741 | 0.89 | CA12 (0.45) | CA12CA1CA2CA9PPARD | |
| SCHEMBL3346379 | 0.85 | CA12 (0.44) | CA12CA1CA2CA9PPARD | |
| SCHEMBL3345630 | 0.82 | PPARD (0.46) | CA12CA1CA2CA9PPARD | |
| SCHEMBL16384701 | 0.78 | TSHR (0.42) | CA12CA1CA2CA9PPARD | |
| SCHEMBL812188 | 0.77 | LPAR3 (0.49) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL28707552 | 0.77 | LPAR3 (0.49) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL3371494 | 0.77 | LPAR3 (0.49) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8847181 | 0.76 | LPAR3 (0.43) | CA12CA1CA2CA9 | |
| SCHEMBL4229904 | 0.76 | CA12 (0.51) | CA12CA1CA2CA9PPARD | |
| SCHEMBL8975603 | 0.76 | CA12 (0.40) | CA12CA1CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414385-B1 | ONE-PART SELF-PRIMING DENTAL ADHESIVE | DENTSPLY INT INC (US) | 2006-12-20 | — | — | EP | disclosed |
| US-6812266-B2 | FOR BONDING DENTAL RESTORATIVES TO DENTIN AND ENAMEL | DENTSPLY DETREY GMBH (DE) | 2004-11-02 | — | — | US | disclosed |
| EP-1414385-A1 | ONE-PART SELF-PRIMING DENTAL ADHESIVE | DENTSPLY INTERNATIONAL, INC. (US) | 2004-05-06 | — | — | EP | disclosed |
| US-20030055124-A1 | Hydrolysis stable one-part self-etching, self-priming dental adhesive | DENTSPLY DETREY GMBH (DE) | 2003-03-20 | — | — | US | disclosed |
| WO-2003013444-A1 | ONE-PART SELF-PRIMING DENTAL ADHESIVE | DENTSPLY INTERNATIONAL INC. (US) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055124-A1 | Hydrolysis stable one-part self-etching, self-priming dental adhesive | PDAP1, CDH1, DPEP1 | CA12 777/4885CA1 59/4885CA2 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.