Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371494 | 1.00 | LPAR3 (0.49) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL28707552 | 1.00 | LPAR3 (0.49) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL8847181 | 0.93 | LPAR3 (0.43) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL15785207 | 0.89 | SAT1 (0.44) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| Trimethylammonium SCHEMBL28395649 | 0.89 | LPAR3 (0.40) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL16384827 | 0.88 | LPAR3 (0.39) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL907411 | 0.86 | LPAR2 (0.42) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL20385669 | 0.86 | PLA2G2A (0.38) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL26757862 | 0.85 | CA12 (0.37) | LPAR3LPAR2LPAR1S1PR2S1PR1 | |
| SCHEMBL12643043 | 0.83 | TSHR (0.47) | KDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111040198-B | DNA hydrogel, preparation method and application thereof | 苏州珀罗汀生物技术有限公司 | 2021-08-17 | — | — | CN | claimed |
| EP-2578201-B1 | Dental materials with improved hydrolysis stability on the basis of phthalic acid monomers | IVOCLAR VIVADENT AG (LI) | 2020-11-25 | — | — | EP | claimed |
| US-10667993-B2 | Polymerizable compositions based on thermally cleavable compounds | IVOCLAR VIVADENT AG (LI) | 2020-06-02 | — | — | US | claimed |
| EP-3156031-B9 | POLYMERISABLE COMPOSITIONS BASED ON THERMALLY CLEAVABLE COMPOUNDS | IVOCLAR VIVADENT AG (LI) | 2020-03-18 | — | — | EP | claimed |
| EP-3156031-B1 | POLYMERISABLE COMPOSITIONS BASED ON THERMALLY CLEAVABLE COMPOUNDS | IVOCLAR VIVADENT AG (LI) | 2019-08-28 | — | — | EP | claimed |
| EP-2753291-B1 | DENTAL MATERIALS BASED ON COMPOUNDS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2019-06-19 | — | — | EP | claimed |
| EP-2753290-B1 | DENTAL MATERIALS ON THE BASIS OF MONOMERS WITH DEBONDING ON DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2019-06-12 | — | — | EP | claimed |
| EP-2755624-B1 | DENTAL MATERIAL BASED ON STRONGLY ACIDIC POLYMERISABLE BISPHOSPHONIC ACIDS | IVOCLAR VIVADENT AG (LI) | 2018-11-14 | — | — | EP | claimed |
| US-20180200155-A1 | Polymerizable Compositions Based On Thermally Cleavable Compounds | IVOCLAR VIVADENT AG (LI) | 2018-07-19 | — | — | US | claimed |
| US-9668946-B2 | Dental materials based on monomers having debonding-on-demand properties | IVOCLAR VIVADENT AG (LI) | 2017-06-06 | — | — | US | claimed |
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | IVOCLAR VIVADENT AG (LI) | 2014-10-02 | — | — | US | claimed |
| US-20130090404-A1 | Dental materials with improved hydrolysis stability based on phthalic acid monomers | IVOCLAR VIVADENT AG (LI) | 2013-04-11 | — | — | US | claimed |
| EP-2578201-A1 | Dental materials with improved hydrolysis stability on the basis of phthalic acid monomers | Ivoclar Vivadent AG (LI) | 2013-04-10 | — | — | EP | claimed |
| WO-2013034777-A2 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2013-03-14 | — | — | WO | claimed |
| WO-2013034778-A2 | DENTAL MATERIALS BASED ON COMPOUNDS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2013-03-14 | — | — | WO | claimed |
| US-8367748-B2 | Surface-modified fillers | IVOCLAR VIVADENT AG (LI) | 2013-02-05 | — | — | US | claimed |
| US-7714034-B2 | Photopolymerizable dental materials with bisacylphosphine oxides as initiators | IVOCLAR VIVADENT AG (LI) | 2010-05-11 | — | — | US | claimed |
| EP-1749513-B1 | Photopolymerisable dental material with bisacylphosphine oxides as initiator | IVOCLAR VIVADENT AG (LI) | 2009-03-04 | — | — | EP | claimed |
| EP-1749513-A1 | Photopolymerisable dental material with bisacylphosphine oxides as inhibitors | Ivoclar Vivadent AG (LI) | 2007-02-07 | — | — | EP | claimed |
| US-20070027229-A1 | Photopolymerizable dental materials with bisacylphosphine oxides as initiators | IVOCLAR VIVADENT AG (LI) | 2007-02-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296364-A1 | Dental Materials on the Basis of Highly Acidic Polymerizable Bisphosphonic Acids | PHOSPHO1, PTK2, ITGA1 | LPAR3 1675/4885LPAR2 1838/4885LPAR1 1298/4885 |
| US-20180200155-A1 | Polymerizable Compositions Based On Thermally Cleavable Compounds | CAD, TERB1, MLX | LPAR3 4648/4885LPAR2 4829/4885LPAR1 4762/4885 |
| US-10667993-B2 | Polymerizable compositions based on thermally cleavable compounds | CAD, TERB1, MLX | LPAR3 4648/4885LPAR2 4829/4885LPAR1 4762/4885 |
| US-20130090404-A1 | Dental materials with improved hydrolysis stability based on phthalic acid monomers | RCOR1, SMC4, RER1 | LPAR3 2130/4885LPAR2 3234/4885LPAR1 2809/4885 |
| US-20070027229-A1 | Photopolymerizable dental materials with bisacylphosphine oxides as initiators | PRXL2A, PGM2, PAM | LPAR3 279/4885LPAR2 822/4885LPAR1 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.