Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 6/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3876773 | 0.77 | L3MBTL1 (0.40) | MAPTPOLBALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL3886270 | 0.72 | RAB9A (0.45) | MAPTPOLBALDH1A1TDP1THRB | |
| SCHEMBL3884667 | 0.70 | RAB9A (0.45) | MAPTPOLBALDH1A1TDP1THRB | |
| SCHEMBL3879057 | 0.69 | MAPT (0.40) | MAPTPOLBALDH1A1HSD17B10ESR2 | |
| SCHEMBL3882583 | 0.69 | ALDH1A1 (0.44) | MAPTPOLBALDH1A1HSD17B10PKM | |
| SCHEMBL3876292 | 0.67 | ALDH1A1 (0.38) | MAPTPOLBALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL3885247 | 0.67 | IDO1 (0.39) | MAPTPOLBALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL6912345 | 0.66 | GAA (0.41) | MAPTALDH1A1TSHRHPGDLMNA | |
| SCHEMBL3884425 | 0.66 | L3MBTL1 (0.40) | MAPTPOLBALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL3875812 | 0.66 | MAPK3 (0.45) | MAPTALDH1A1TDP1HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735059-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005099656-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |