Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6102049 | 0.91 | THRB (0.41) | KDM4EALDH1A1POLBTHRBHRH2 | |
| SCHEMBL6102002 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL5714085 | 0.86 | THRB (0.40) | ALDH1A1POLBTHRBHRH2HRH1 | |
| SCHEMBL5714864 | 0.86 | THRB (0.42) | KDM4EALDH1A1POLBTHRBDRD2 | |
| SCHEMBL5714157 | 0.83 | KDM4E (0.46) | KDM4EALDH1A1HRH2HRH1DRD2 | |
| SCHEMBL5715611 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1LMNAPOLBTHRB | |
| SCHEMBL5714791 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1LMNAPOLBTHRB | |
| SCHEMBL5715063 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL5714519 | 0.81 | SLC6A5 (0.49) | KDM4EALDH1A1LMNAPOLBSLC6A5 | |
| SCHEMBL5715250 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1LMNAPOLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006527212-A | — | — | 2006-11-30 | — | — | JP | claimed |
| EP-1636187-A1 | SUBSTITUTED PIPERAZINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2006-03-22 | — | — | EP | claimed |
| WO-2004111004-A1 | SUBSTITUTED PIPERAZINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-12-23 | — | — | WO | claimed |
| EP-1636187-A1 | SUBSTITUTED PIPERAZINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004111004-A1 | SUBSTITUTED PIPERAZINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-12-23 | — | — | WO | disclosed |