Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MDH1 | P40925 | 1/20 | 0.40 |
| ▸ | MDH2 | P40926 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6102639 | 0.90 | TRPA1 (0.45) | SLC6A5TRPA1TRPV1MDH1MDH2 | |
| SCHEMBL5715611 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1LMNAPOLBLTA4H | |
| SCHEMBL6102857 | 0.86 | HIF1A (0.59) | SLC6A5HIF1AEPAS1FAAHKDM4E | |
| SCHEMBL5714791 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL6101710 | 0.84 | TRPV1 (0.50) | SLC6A5HIF1AEPAS1FAAHTRPA1 | |
| SCHEMBL5715602 | 0.84 | LIPE (0.44) | TRPA1TRPV1 | |
| SCHEMBL5714649 | 0.83 | KDM4E (0.46) | KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL5715250 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL5714710 | 0.81 | KDM4E (0.43) | SLC6A5KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL6103199 | 0.81 | TRPV1 (0.48) | SLC6A5HIF1AEPAS1FAAHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006527212-A | — | — | 2006-11-30 | — | — | JP | claimed |
| EP-1636187-A1 | SUBSTITUTED PIPERAZINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2006-03-22 | — | — | EP | claimed |
| WO-2004111004-A1 | SUBSTITUTED PIPERAZINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-12-23 | — | — | WO | claimed |
| EP-1636187-A1 | SUBSTITUTED PIPERAZINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004111004-A1 | SUBSTITUTED PIPERAZINE CARBAMATES FOR USE AS INHIBITORS OF HORMONE SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-12-23 | — | — | WO | disclosed |