SCHEMBL5715848

SCHEMBL5715848

CCCCCCP(CCC)c1cccc(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ICMT O60725 2/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KCNH2 Q12809 2/20 0.36
EPHX2 P34913 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
PLK1 P53350 1/20 0.31
CES2 O00748 1/20 0.31
BCHE P06276 1/20 0.31
CES1 P23141 1/20 0.31
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6444251 1.00 ICMT (0.39) ICMTMEN1KMT2ASMN1; SMN2KCNH2
SCHEMBL5716047 0.97 ICMT (0.38) ICMTMEN1KMT2ASMN1; SMN2KCNH2
SCHEMBL6797541 0.93 ICMT (0.35) ICMTMEN1KMT2ASMN1; SMN2KCNH2
SCHEMBL5716604 0.90 ICMT (0.36) ICMTMEN1KMT2ASMN1; SMN2KCNH2
SCHEMBL5716139 0.90 ICMT (0.36) ICMTMEN1KMT2ASMN1; SMN2KCNH2
SCHEMBL5716289 0.84 PRSS1 (0.33) ICMTMEN1KMT2ASMN1; SMN2KCNH2
SCHEMBL5715616 0.83 HDAC3 (0.35) ICMTMEN1KMT2ASMN1; SMN2KCNH2
SCHEMBL7612849 0.83 SMN1; SMN2 (0.36) ICMTMEN1KMT2ASMN1; SMN2KCNH2
SCHEMBL5716082 0.83 CES2 (0.34) ICMTHDAC3HDAC1HDAC2HDAC8
SCHEMBL5716176 0.82 ICMT (0.37) ICMTMEN1KMT2ASMN1; SMN2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed