SCHEMBL6797541

SCHEMBL6797541

CCCCP(CCC)c1cccc(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ICMT O60725 1/20 0.35
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CES2 O00748 1/20 0.32
BCHE P06276 1/20 0.32
CES1 P23141 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6444251 0.93 ICMT (0.39) ICMTHDAC3HDAC1HDAC2HDAC8
SCHEMBL5715848 0.93 ICMT (0.39) ICMTHDAC3HDAC1HDAC2HDAC8
SCHEMBL5715616 0.90 HDAC3 (0.35) ICMTHDAC3HDAC1HDAC2HDAC8
SCHEMBL5716047 0.90 ICMT (0.38) ICMTHDAC3HDAC1HDAC2HDAC8
SCHEMBL5716082 0.86 CES2 (0.34) ICMTHDAC3HDAC1HDAC2HDAC8
SCHEMBL5716139 0.83 ICMT (0.36) ICMTHDAC3HDAC1HDAC2HDAC8
SCHEMBL5716604 0.83 ICMT (0.36) ICMTHDAC3HDAC1HDAC2HDAC8
SCHEMBL5715873 0.81
SCHEMBL5716289 0.78 PRSS1 (0.33) ICMTMEN1KMT2ASMN1; SMN2KCNH2
SCHEMBL7612849 0.75 SMN1; SMN2 (0.36) ICMTHDAC3HDAC1HDAC2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed