SCHEMBL5715928

SCHEMBL5715928

CC(=O)N1C(C)(C)CCC(O)C1(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
EPHX2 P34913 1/20 0.31
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5774163 0.84
SCHEMBL14369404 0.73 ESR1 (0.41) SMN1; SMN2L3MBTL1EPHX2ESR1
SCHEMBL379399 0.72 GAA (0.37) GAAL3MBTL1
SCHEMBL4449961 0.70 GAA (0.60) GAAL3MBTL1
SCHEMBL2678629 0.70 GAA (0.38) GAAL3MBTL1
SCHEMBL8613670 0.69 TSHR (0.43) SMN1; SMN2L3MBTL1ESR1
SCHEMBL10574423 0.69 TSHR (0.43) SMN1; SMN2L3MBTL1ESR1
SCHEMBL9168096 0.69 EPHX2 (0.31) EPHX2
SCHEMBL28277841 0.68 GAA (0.37) GAAL3MBTL1
SCHEMBL16566503 0.68 SPHK1 (0.33) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1681046-A2 Cosmetic, pharmaceutical and dermatological compositions containing copolymer waxes Clariant Produkte (Deutschland) GmbH (DE) 2006-07-19 EP claimed
US-20060036013-A1 Side-chain-modified copolymer waxes HEINRICHS FRANZ-LEO 2006-02-16 US claimed
CN-1659191-A Side-chain-modified copolymer waxes CLARIANT GMBH (DE) 2005-08-24 CN claimed
EP-1523507-A1 SIDE-CHAIN-MODIFIED COPOLYMER WAXES Clariant GmbH (DE) 2005-04-20 EP claimed
WO-2003104289-A1 SIDE-CHAIN-MODIFIED COPOLYMER WAXES CLARIANT GMBH (DE) 2003-12-18 WO claimed
CN-1284803-C Side-chain-modified copolymer waxes CLARIANT GMBH (DE) 2006-11-15 CN disclosed
EP-1681046-A2 Cosmetic, pharmaceutical and dermatological compositions containing copolymer waxes Clariant Produkte (Deutschland) GmbH (DE) 2006-07-19 EP disclosed
US-20060104940-A1 Cosmetic, pharmaceutical and dermatological preparations comprising copolymer waxes CLARIANT GMBH 2006-05-18 US disclosed
US-20060036013-A1 Side-chain-modified copolymer waxes HEINRICHS FRANZ-LEO 2006-02-16 US disclosed
CN-1659191-A Side-chain-modified copolymer waxes CLARIANT GMBH (DE) 2005-08-24 CN disclosed
EP-1523507-A1 SIDE-CHAIN-MODIFIED COPOLYMER WAXES Clariant GmbH (DE) 2005-04-20 EP disclosed
WO-2003104289-A1 SIDE-CHAIN-MODIFIED COPOLYMER WAXES CLARIANT GMBH (DE) 2003-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060104940-A1 Cosmetic, pharmaceutical and dermatological preparations comprising copolymer waxes CUTA, ACMSD, DEGS1 SMN1; SMN2 3699/4885GAA 1124/4885L3MBTL1 4705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.