Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25183891 | 0.90 | CA1 (0.49) | HDAC3HDAC8HDAC6EPHX2NR1H4 | |
| SCHEMBL17864362 | 0.84 | THRB (0.48) | HDAC3HDAC8HDAC6EPHX2NR1H4 | |
| SCHEMBL20902781 | 0.81 | CA1 (0.65) | HDAC3HDAC8HDAC6EPHX2NR1H4 | |
| SCHEMBL178541 | 0.79 | EPHX2 (0.53) | HDAC3HDAC8HDAC6EPHX2NR1H4 | |
| SCHEMBL18025774 | 0.77 | IDO1 (0.50) | HDAC3HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL11147050 | 0.77 | GABRA1 (0.46) | HDAC3HDAC8HDAC6THRBIDO1 | |
| SCHEMBL21192809 | 0.77 | EPHX2 (0.47) | HDAC3HDAC8HDAC6EPHX2NR1H4 | |
| SCHEMBL25381118 | 0.77 | CA1 (0.58) | HDAC3HDAC8HDAC6EPHX2NR1H4 | |
| SCHEMBL11621318 | 0.77 | CA1 (0.56) | HDAC3HDAC8HDAC6EPHX2NR1H4 | |
| SCHEMBL13208251 | 0.77 | EPHX2 (0.47) | HDAC3HDAC8HDAC6EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558574-A4 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO LTD (KR) | 2006-06-21 | — | — | EP | disclosed |
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | DIGITAL BIOTECH CO., LTD. (KR) | 2005-12-29 | — | — | US | disclosed |
| EP-1558574-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Digital Biotech Co., Ltd. (KR) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004035533-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO., LTD. (KR) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | HRH2, HRH4, NMUR2 | HDAC3 3613/4885HDAC8 1172/4885HDAC6 2324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.