Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL7742046 | 0.96 | SIGMAR1 (0.59) | DRD2DRD4DRD3SIGMAR1KDM4E | |
| Biphenyl SCHEMBL5715930 | 0.92 | SIGMAR1 (0.61) | DRD2DRD4DRD3SIGMAR1HRH4 | |
| Biphenyl SCHEMBL12984111 | 0.91 | DRD2 (0.56) | DRD2DRD4DRD3SIGMAR1HDAC3 | |
| Biphenyl SCHEMBL22832517 | 0.87 | SIGMAR1 (0.66) | DRD2DRD4DRD3SIGMAR1HRH4 | |
| Biphenyl SCHEMBL5716029 | 0.87 | SIGMAR1 (0.66) | DRD2DRD4DRD3SIGMAR1HRH4 | |
| Biphenyl SCHEMBL27827416 | 0.85 | SIGMAR1 (0.63) | DRD2DRD4DRD3SIGMAR1HRH4 | |
| SCHEMBL11336635 | 0.84 | NOTUM (0.56) | DRD2DRD4DRD3SIGMAR1KDM4E | |
| SCHEMBL21357863 | 0.84 | HRH4 (0.61) | DRD2DRD4DRD3SIGMAR1HDAC3 | |
| Biphenyl SCHEMBL5716479 | 0.83 | SIGMAR1 (0.47) | DRD2DRD4DRD3SIGMAR1KDM4E | |
| Biphenyl SCHEMBL7608054 | 0.82 | DRD2 (0.48) | DRD2DRD4DRD3SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661900-A1 | Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them | ExxonMobil Chemical Patents Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1252166-B1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXONMOBIL CHEM PATENTS INC (US) | 2005-11-09 | — | — | EP | disclosed |