Biphenyl

Biphenyl

SCHEMBL5715930

CCCCCCCCCNCCC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.61
DRD2 P14416 1/20 0.59
DRD4 P21917 1/20 0.59
DRD3 P35462 1/20 0.59
HRH4 Q9H3N8 1/20 0.53
HRH3 Q9Y5N1 1/20 0.53
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
CHRM2 P08172 1/20 0.48
NAAA Q02083 1/20 0.47
GRIN1 Q05586 2/20 0.46
GRIN2A Q12879 2/20 0.46
SOAT1 P35610 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL22832517 0.96 SIGMAR1 (0.66) SIGMAR1DRD2DRD4DRD3HRH4
Biphenyl SCHEMBL5716029 0.96 SIGMAR1 (0.66) SIGMAR1DRD2DRD4DRD3HRH4
Biphenyl SCHEMBL27827416 0.94 SIGMAR1 (0.63) SIGMAR1DRD2DRD4DRD3HRH4
Biphenyl SCHEMBL5716264 0.92 DRD2 (0.58) SIGMAR1DRD2DRD4DRD3HRH4
Biphenyl SCHEMBL5716055 0.88 SIGMAR1 (0.56) SIGMAR1DRD2DRD4DRD3HRH4
Biphenyl SCHEMBL7742046 0.87 SIGMAR1 (0.59) SIGMAR1DRD2DRD4DRD3HRH4
Biphenyl SCHEMBL12984111 0.87 DRD2 (0.56) SIGMAR1DRD2DRD4DRD3ALDH1A1
Biphenyl SCHEMBL5716585 0.85 SIGMAR1 (0.53) SIGMAR1DRD2DRD4DRD3HRH4
Benzene SCHEMBL28999857 0.82 TSHR (0.77) SIGMAR1HRH4HRH3ALDH1A1TSHR
Biphenyl SCHEMBL5868587 0.82 ALDH1A1 (0.53) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed