Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL5716337 | 0.88 | NPC1 (0.35) | NPC1RAB9ASIGMAR1CYP17A1 | |
| Biphenyl SCHEMBL5715905 | 0.87 | NPC1 (0.39) | NPC1RAB9ACYP17A1HTTPOLB | |
| Biphenyl SCHEMBL5716559 | 0.82 | ALDH1A1 (0.38) | NPC1RAB9ASIGMAR1CYP17A1MAPT | |
| Biphenyl SCHEMBL28094047 | 0.78 | ALDH1A1 (0.47) | NPC1RAB9ASIGMAR1SMN1; SMN2MAPT | |
| SCHEMBL7616635 | 0.75 | GCGR (0.37) | MAPTL3MBTL1ALDH1A1 | |
| Biphenyl SCHEMBL27492665 | 0.72 | NPC1 (0.49) | NPC1RAB9ASIGMAR1CYP17A1SMN1; SMN2 | |
| Biphenyl SCHEMBL5716199 | 0.71 | ALDH1A1 (0.39) | NPC1RAB9ASIGMAR1SMN1; SMN2MAPT | |
| Biphenyl SCHEMBL7650991 | 0.71 | HDAC3 (0.41) | SMN1; SMN2MAPTPOLBHPGDL3MBTL1 | |
| SCHEMBL10720375 | 0.70 | SIGMAR1 (0.46) | NPC1RAB9ASIGMAR1 | |
| Biphenyl SCHEMBL5715691 | 0.70 | NPC1 (0.36) | NPC1RAB9ACYP17A1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661900-A1 | Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them | ExxonMobil Chemical Patents Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1252166-B1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXONMOBIL CHEM PATENTS INC (US) | 2005-11-09 | — | — | EP | disclosed |