Biphenyl

Biphenyl

SCHEMBL5716337

CCCPCC(C)CCC(CC)CCC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SIGMAR1 Q99720 1/20 0.31
TRPA1 O75762 1/20 0.30
CYP17A1 P05093 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL5716281 0.88 NPC1 (0.40) NPC1RAB9ASIGMAR1CYP17A1
SCHEMBL5716512 0.86
Biphenyl SCHEMBL5715691 0.85 NPC1 (0.36) NPC1RAB9ATRPA1CYP17A1
Biphenyl SCHEMBL5716559 0.83 ALDH1A1 (0.38) NPC1RAB9ASIGMAR1CYP17A1
Biphenyl SCHEMBL5716483 0.76 ALDH1A1 (0.41) NPC1RAB9ASIGMAR1TRPA1CYP17A1
Biphenyl SCHEMBL5715905 0.76 NPC1 (0.39) NPC1RAB9ACYP17A1
Biphenyl SCHEMBL5715585 0.73 NPC1 (0.38) NPC1RAB9ASIGMAR1
Biphenyl SCHEMBL5716100 0.72 NPC1 (0.37) NPC1RAB9ASIGMAR1
Biphenyl SCHEMBL6795603 0.72 NPC1 (0.33) NPC1RAB9A
Biphenyl SCHEMBL5716397 0.71 KDM4E (0.41) NPC1RAB9ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed