SCHEMBL8965241

SCHEMBL8965241

O=C1CCC(=O)N1c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.65
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA9 Q16790 2/20 0.52
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 3/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
ALOX12 P18054 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
MAPK1 P28482 1/20 0.50
PTGS2 P35354 1/20 0.50
HTR2B P41595 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KMT2A Q03164 5/20 0.49
MEN1 O00255 2/20 0.48
GFER P55789 1/20 0.48
POLB P06746 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24259899 0.92 CA12 (0.53) HSP90AA1CA12CA1CA9ALDH1A1
SCHEMBL370611 0.81 KMT2A (0.64) CA12CA1CA9ALDH1A1HSD17B10
SCHEMBL571682 0.78 HSP90AA1 (1.00) HSP90AA1ALDH1A1HSD17B10ALOX15TSHR
SCHEMBL11478927 0.78 CA12 (0.67) CA12CA1CA9ALDH1A1L3MBTL1
SCHEMBL24641959 0.78 ALDH1A1 (0.53) CA12CA1CA9ALDH1A1TSHR
SCHEMBL2132967 0.77 KMT2A (0.68) HSP90AA1CA12CA1CA9ALDH1A1
SCHEMBL8995947 0.76 HSP90AA1 (0.54) HSP90AA1ALDH1A1HSD17B10ALOX15TSHR
SCHEMBL4685693 0.76 CA12 (0.53) CA12CA1CA9ALDH1A1HSD17B10
SCHEMBL7498377 0.74 KMT2A (0.42) HSP90AA1ALDH1A1HSD17B10ALOX15TSHR
SCHEMBL10189790 0.74 GAA (0.74) HSP90AA1ALDH1A1HSD17B10TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0446510-B1 Stable middle distillate fuel-oil compositions TEXACO DEVELOPMENT CORP (US) 1993-10-20 EP claimed
EP-0446510-A1 Stable middle distillate fuel-oil compositions TEXACO DEVELOPMENT CORPORATION (US) 1991-09-18 EP claimed
US-4919683-A CONTAINING AS STORAGE STABILIZER A COPOLYMER GRAFTED WITH AN AROMATIC POLYAMINE SUCCINIMIDE TEXACO INC. (US) 1990-04-24 US claimed
US-20210309846-A1 ACRYLIC COPOLYMER AND RUBBER MATERIAL OSAKA SODA CO., LTD. (JP) 2021-10-07 US disclosed
EP-0510892-B1 Method for retarding darkening of a dispersant-antioxidant olefin copolymer TEXACO DEVELOPMENT CORP (US) 1996-02-28 EP disclosed
US-5207938-A METHOD FOR RETARDING DARKENING OF A DISPERSANT-ANTIOXIDANT OLEFIN COPOLYMER TEXACO INC. (US) 1993-05-04 US disclosed
EP-0510892-A1 Method for retarding darkening of a dispersant-antioxidant olefin copolymer TEXACO DEVELOPMENT CORPORATION (US) 1992-10-28 EP disclosed
US-4919683-A CONTAINING AS STORAGE STABILIZER A COPOLYMER GRAFTED WITH AN AROMATIC POLYAMINE SUCCINIMIDE TEXACO INC. (US) 1990-04-24 US disclosed