Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5716963 | 0.88 | LMNA (0.50) | LMNAKMT2AMEN1HSD17B10ALDH1A1 | |
| SCHEMBL5716847 | 0.86 | LMNA (0.42) | LMNAKMT2AMEN1HSD17B10ALDH1A1 | |
| SCHEMBL5716948 | 0.83 | LMNA (0.43) | LMNAKMT2AMEN1HSD17B10ALDH1A1 | |
| SCHEMBL5716938 | 0.81 | LMNA (0.39) | LMNAKMT2AMEN1HSD17B10ALDH1A1 | |
| SCHEMBL5466341 | 0.81 | LMNA (0.39) | LMNAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL5716934 | 0.79 | LMNA (0.47) | LMNAKMT2AMEN1HSD17B10ALDH1A1 | |
| SCHEMBL5716943 | 0.77 | POLQ (0.46) | LMNAKMT2AMEN1L3MBTL1TAS2R14 | |
| SCHEMBL5380338 | 0.69 | POLB (0.56) | LMNAKMT2AMEN1HSD17B10ALDH1A1 | |
| SCHEMBL4904188 | 0.69 | LMNA (0.53) | LMNAKMT2AMEN1HSD17B10ALDH1A1 | |
| SCHEMBL5716951 | 0.69 | LMNA (0.50) | LMNAKMT2AMEN1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725524-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | Pfizer Products Incorporated (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005092845-A1 | SUBSTITUTED HETEROARYL- AND PHENYLSULFAMOYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2005-10-06 | — | — | WO | disclosed |