Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5403419 | 0.90 | GAA (0.42) | KMT2AGAANAMPTPOLBALDH1A1 | |
| SCHEMBL5716889 | 0.81 | LMNA (0.47) | LMNAKMT2APOLBTAS2R14MEN1 | |
| SCHEMBL5374543 | 0.81 | POLB (0.43) | LMNAKMT2AGAANAMPTPOLB | |
| SCHEMBL5716847 | 0.80 | LMNA (0.42) | LMNAKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL5716963 | 0.80 | LMNA (0.50) | LMNAKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL5716948 | 0.78 | LMNA (0.43) | LMNAKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL5395468 | 0.74 | LMNA (0.45) | LMNAKMT2AGAANAMPTPOLB | |
| SCHEMBL5716938 | 0.72 | LMNA (0.39) | LMNAKMT2APOLBTAS2R14MEN1 | |
| SCHEMBL5716943 | 0.69 | POLQ (0.46) | LMNAKMT2ATAS2R14MEN1 | |
| SCHEMBL4905703 | 0.66 | LMNA (0.62) | LMNAKMT2APOLBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |