Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aristolochic Acid Ii SCHEMBL29518307 | 1.00 | CDK2 (0.77) | CDK2ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| Aristolochic Acid C SCHEMBL30039516 | 0.87 | CDK2 (1.00) | CDK2ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| Aristolochic Acid C SCHEMBL30697302 | 0.87 | CDK2 (1.00) | CDK2ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| Aristolochic Acid Iii SCHEMBL30568104 | 0.84 | CDK2 (1.00) | CDK2ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7456768 | 0.83 | CDK2 (0.68) | CDK2ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| Aristolochic Acid SCHEMBL30825061 | 0.81 | ALDH1A1 (1.00) | CDK2ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| Aristolochic Acid SCHEMBL29367530 | 0.81 | ALDH1A1 (1.00) | CDK2ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| Aristolochic Acid SCHEMBL29518476 | 0.81 | ALDH1A1 (1.00) | CDK2ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| Aristolochic Acid SCHEMBL15535358 | 0.80 | ALDH1A1 (0.98) | CDK2ALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| 7-Hydroxy Aristolochic A SCHEMBL4557492 | 0.76 | CDK2 (1.00) | CDK2ALDH1A1MAPTCYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4714440-A2 | A HEALING HERBAL-MINERAL COMPOSITION WITH ENHANCED EFFECTS | Kurek, Janusz (PL) | 2026-03-25 | — | — | EP | claimed |
| CN-114624376-B | Method for detecting aristolochic acid I-DNA adducts in tissues | 中国科学院上海药物研究所 | 2024-10-11 | — | — | CN | claimed |
| CN-117471003-B | Separation and quantitative detection method for aristolochic acid component in houttuynia cordata and application thereof | 中国中医科学院中药研究所 | 2024-10-08 | — | — | CN | claimed |
| CN-117517537-B | Method for detecting aristolochic acid in Baicao oil based on elimination of matrix effect | 山东省食品药品检验研究院 | 2024-09-17 | — | — | CN | claimed |
| CN-114200059-B | Method for rapidly screening toxic alkaloids in Chinese herbal medicine based on UPLC-QTOF-MS technology combined UNIFI | 福州大学 | 2024-07-05 | — | — | CN | claimed |
| CN-117805273-B | Quantitative detection method and application of 5 aristolochic acid substances in diarrhea-relieving capsule | 浙江苏可安药业有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-117805273-A | Quantitative detection method and application of 5 aristolochic acid substances in diarrhea-relieving capsule | 浙江苏可安药业有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117517537-A | Method for detecting aristolochic acid in Baicao oil based on elimination of matrix effect | 山东省食品药品检验研究院 | 2024-02-06 | — | — | CN | claimed |
| CN-117471003-A | Separation and quantitative detection method for aristolochic acid component in houttuynia cordata and application thereof | 中国中医科学院中药研究所 | 2024-01-30 | — | — | CN | claimed |
| CN-116678968-A | Method for detecting various toxic components in traditional Chinese medicine | 广东省药品检验所（广东省药品质量研究所、广东省口岸药品检验所） | 2023-09-01 | — | — | CN | claimed |
| CN-114624376-A | Method for detecting aristolochic acid I-DNA adduct in tissue | 中国科学院上海药物研究所 | 2022-06-14 | — | — | CN | claimed |
| CN-114487203-A | Method for detecting aristolochic acid in houttuynia cordata based on metal organic framework material dispersion solid-phase extraction combined with high performance liquid chromatography | 南昌大学 | 2022-05-13 | — | — | CN | claimed |
| CN-113846038-A | Arthrobacter strain and application thereof in degradation of aristolochic acid | 上海交通大学 | 2021-12-28 | — | — | CN | claimed |
| CN-113063862-A | Method for simultaneously detecting 4 aristolochic acid substances in houttuynia cordata based on ultra-high performance liquid chromatography-mass spectrometry | 南昌大学 | 2021-07-02 | — | — | CN | claimed |
| CN-110194758-B | Method for separating and purifying aristolochic acid compounds from caulis Aristolochiae Manshuriensis | 山东省分析测试中心 | 2020-12-01 | — | — | CN | claimed |
| CN-111141852-A | Method for accurately quantifying carcinogenic aristolochic acid in traditional Chinese medicine | 齐鲁工业大学 | 2020-05-12 | — | — | CN | claimed |
| CN-110194758-A | A method of the fast separating and purifying Aristolochic Acid compound from caulis aristologhiae manshuriensis | 山东省分析测试中心 | 2019-09-03 | — | — | CN | claimed |
| CN-108918460-A | A method of based on aristolochic acid I content in near-infrared spectrum technique measurement Chinese medicine | 福建医科大学 | 2018-11-30 | — | — | CN | claimed |
| CN-100570354-C | Method by 3,4-methylenedioxy-8-methoxy-10-nitro-1-phenanthrenecarboxylic acid and aristolochic acid II content in the Capillary Zone Electrophoresis with Electrochemical analytical technology mensuration Chinese herbal medicine | CHANGCHUN APPLIED CHEMISTRY (CN) | 2009-12-16 | — | — | CN | claimed |
| CN-1959408-A | Method for mensurating in vivo sample of containing aristolochic acid and components of lactam categories | UNIV BEIJING (CN) | 2007-05-09 | — | — | CN | claimed |