Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 11/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.57 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717045 | 0.85 | FKBP1A (0.64) | FKBP1AHCRTR1HCRTR2KMT2AALDH1A1 | |
| SCHEMBL5717188 | 0.84 | FKBP1A (0.63) | FKBP1AKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL5717081 | 0.84 | FKBP1A (0.62) | FKBP1AKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL5716995 | 0.82 | FKBP1A (0.60) | FKBP1AKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL5717227 | 0.82 | ALDH1A1 (0.64) | FKBP1AHCRTR1HCRTR2KMT2AALDH1A1 | |
| SCHEMBL24072630 | 0.82 | RAB9A (0.64) | FKBP1AKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL5717102 | 0.82 | ALDH1A1 (0.64) | FKBP1AHCRTR1HCRTR2KMT2AALDH1A1 | |
| SCHEMBL5717100 | 0.82 | ALDH1A1 (0.64) | FKBP1AHCRTR1HCRTR2KMT2AALDH1A1 | |
| SCHEMBL6801501 | 0.81 | FKBP1A (0.66) | FKBP1AKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL20291018 | 0.81 | ALDH1A1 (0.60) | FKBP1AKMT2AALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664010-A1 | SULFONAMIDES ANTAGONISING N-TYPE CALCIUM CHANNELS | Vernalis (R&D) Limited (GB) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005068448-A1 | SULFONAMIDES ANTAGONISING N-TYPE CALCIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-07-28 | — | — | WO | disclosed |