Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717998 | 0.92 | THRB (0.36) | THRATHRBKDM4EALDH1A1LMNA | |
| SCHEMBL4530626 | 0.86 | THRB (0.35) | THRATHRBKDM4EALDH1A1LMNA | |
| SCHEMBL4932175 | 0.86 | THRB (0.39) | THRATHRBKDM4EALDH1A1LMNA | |
| SCHEMBL5717947 | 0.84 | THRB (0.42) | THRATHRBKDM4EALDH1A1LMNA | |
| SCHEMBL5717941 | 0.83 | THRB (0.52) | THRATHRB | |
| SCHEMBL4349944 | 0.76 | THRA (0.54) | THRATHRB | |
| SCHEMBL4361635 | 0.75 | THRB (0.58) | THRATHRB | |
| SCHEMBL4360479 | 0.74 | THRB (0.45) | THRATHRBKDM4EALDH1A1LMNA | |
| SCHEMBL4348405 | 0.73 | SMN1; SMN2 (0.39) | THRATHRBLMNAKMT2A | |
| SCHEMBL4561844 | 0.73 | THRB (0.37) | THRATHRBKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732533-A1 | THYROID RECEPTOR AGONISTS | KARO BIO AB (SE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092317-A1 | THYROID RECEPTOR AGONISTS | KARO BIO AB (SE) | 2005-10-06 | — | — | WO | disclosed |