Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 5/20 | 0.33 |
| ▸ | GIPR | P48546 | 3/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718010 | 0.87 | LTB4R2 (0.34) | LTB4R2KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5718017 | 0.79 | LTB4R2 (0.40) | LTB4R2GCGRGIPRKCNQ3KCNQ2 | |
| SCHEMBL5864496 | 0.71 | PPARG (0.44) | — | |
| SCHEMBL5864456 | 0.68 | CYP2D6 (0.44) | CHRM1 | |
| SCHEMBL5718013 | 0.66 | KCNQ3 (0.37) | LTB4R2GCGRGIPRKCNQ3KCNQ2 | |
| SCHEMBL5864492 | 0.65 | KDM4E (0.38) | KDM4EALDH1A1 | |
| SCHEMBL5718068 | 0.64 | ATM (0.40) | LTB4R2KCNQ3KCNQ2SLC6A2SLC6A4 | |
| SCHEMBL6733188 | 0.64 | ALDH1A1 (0.40) | LTB4R2SMN1; SMN2KCNQ3KCNQ2SLC6A2 | |
| SCHEMBL6737598 | 0.62 | SLC6A2 (0.45) | KCNQ3KCNQ2SLC6A2SLC6A4 | |
| SCHEMBL5718155 | 0.61 | ALDH1A1 (0.42) | LTB4R2KDM4ECHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318977-B1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-12-06 | — | — | EP | claimed |
| EP-1318977-B1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-12-06 | — | — | EP | disclosed |